Artificial intelligence to detect peripheral artery disease early
Official title: Artificial Intelligence for early Detection of Peripheral Artery Disease (AID-PAD)
Funded at University of California, San Diego · NIH-11394514 · Data updated 2026-11-12
A hospital-based project uses AI to spot peripheral artery disease early in adults using electronic health records so clinicians can start care sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 21, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $468,664 |
| NIH project number | 5R01AG084343-04 |
| Project ID | NIH-11394514 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older who are at risk for PAD and access to the participating healthcare systems.
✕Less likely to help
Patients without access to the participating clinics or those not at risk for PAD may not benefit.
What this research studies
This project will test an AI model built from large electronic health record data to flag people who may have PAD before a clinician diagnoses it. Researchers will validate the model across different clinical sites and patient groups to see how well it works in real-world settings. They will also study how using an AI-based screening tool could fit into clinic workflows and whether it improves patient care. The team aims to understand how best to implement the technology so it benefits diverse patients, including those who are often diagnosed later in the disease course.
Why it matters
Potential benefit: If successful, the AI tool could help clinicians detect PAD earlier, leading to earlier treatment and better outcomes for patients.
How similar studies have gone: Prior studies suggest AI-based screening can improve detection in other conditions; this project builds on that approach for PAD.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Ross, Elsie Gyang — University of California, San Diego
- Study coordinator: Ross, Elsie Gyang
Related research
Other NIH-funded projects on the same topics.
-
Low-dose colchicine to reduce vascular risk in people with peripheral artery disease
This project tests whether taking a low-dose anti-inflammatory drug (colchicine) daily can lower heart and limb-related risks for adults with peripheral artery disease.
-
Gamified home walking program to help seniors with peripheral artery disease improve walking and quality of life
A program uses game elements on wearable devices to help people 65+ with peripheral artery disease walk more at home and feel better.
-
Fatty clues in leg arteries: how fat burning in mitochondria affects PAD and muscle health
This project looks at how fat metabolism in leg muscles relates to weakness and tissue damage in people with peripheral artery disease and aims to find new ways to help them.
-
Enhancing muscle energy to help leg function in PAD
A study to boost how muscle mitochondria work in people with peripheral artery disease to improve walking and leg function.
-
Low-dose colchicine for people with peripheral artery disease to reduce heart and limb risks
A large international study will test whether a low daily dose of colchicine can lower heart and limb complications for people with peripheral artery disease.
-
Low-dose colchicine for reducing vascular risk in people with PAD
A large international study will test whether a daily low dose of colchicine can lower heart and limb-related risks for people with peripheral artery disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.