Analyzing brain cancer using advanced imaging and mathematical models
Official title: Mathematical Oncology Systems Analysis Imaging Center (MOSAIC)
Funded at Mayo Clinic Arizona · NIH-10930911 · Data updated 2026-11-12
This study is looking at glioblastoma, a tough type of brain cancer, to better understand how it grows and changes by using advanced imaging and math, with the goal of creating more personalized treatment options for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,951,992 |
| NIH project number | 5U54CA274504-02 |
| Project ID | NIH-10930911 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing treatment or evaluation.
✕Less likely to help
Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
What this research studies
This research focuses on glioblastoma, a highly aggressive form of brain cancer, by utilizing advanced imaging techniques and mathematical modeling to understand the tumor's cellular composition and behavior. The study aims to integrate spatial and temporal data from MRI scans with molecular analysis of tumor biopsies to create a comprehensive picture of the cancer's evolution. By identifying distinct cellular states within the tumor, researchers hope to develop more precise and personalized treatment strategies for patients. The approach emphasizes the importance of understanding the tumor's complexity to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with glioblastoma.
How similar studies have gone: Previous research has shown promise in using imaging and molecular analysis to understand cancer heterogeneity, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Swanson, Kristin R — Mayo Clinic Arizona
- Study coordinator: Swanson, Kristin R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.