AI-powered tool to diagnose and predict muscle disease in child brain-tumor survivors
Official title: CLinical ChARacterIzation of Treatment-related MorbiditY in Pediatric Brain Tumor Survivors with Artificial Intelligence (CLARITY-AI)
Funded at Brigham and Women's Hospital · NIH-11426745 · Data updated 2026-11-12
A pediatric brain-tumor survivor-focused project will use AI on routine imaging to identify muscle loss and forecast related health problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $815,772 |
| NIH project number | 1R01CA315473-01 |
| Project ID | NIH-11426745 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children, adolescents, and young adults who survived pediatric brain tumors and have ongoing health concerns related to muscle status.
✕Less likely to help
Patients without access to routine imaging or those outside the survivorship care setting may not directly benefit.
What this research studies
This project uses artificial intelligence to analyze standard clinical imaging from children, teens, and young adults who survived brain tumors. It aims to reliably detect sarcopenia early and predict how it may affect their health over time, so clinicians can tailor care. By leveraging existing medical images, the team hopes to create a cost-effective way to monitor muscle status and guide personalized interventions.
Why it matters
Potential benefit: If successful, patients could receive earlier, personalized management to prevent or lessen muscle loss and related complications.
How similar studies have gone: Prior work in other populations suggests AI can identify sarcopenia from imaging, but application in pediatric brain-tumor survivors is novel.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Kann, Benjamin Harris — Brigham and Women's Hospital
- Study coordinator: Kann, Benjamin Harris
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.