AI-powered embryo choice platform to improve IVF outcomes
Official title: AI-Driven Embryo Selection Platform for Enhanced Implantation in IVF: A Phased Development and Randomized Clinical Trial
Funded at Weill Medical Coll of Cornell Univ · NIH-11456701 · Data updated 2026-11-12
A new AI-based system helps doctors choose embryos for IVF, aiming to improve implantation success for couples trying to have a baby.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 15, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $472,674 |
| NIH project number | 1R61HD123536-01 |
| Project ID | NIH-11456701 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are couples undergoing IVF who are eligible for embryo transfer at participating clinics.
✕Less likely to help
Patients not undergoing embryo transfer or whose IVF plans do not involve embryo selection may not benefit.
What this research studies
This project develops and tests a next-generation AI model trained on millions of embryo images to guide embryo selection during IVF. In the initial phase, researchers will train and benchmark robust AI architectures using data from multiple clinics, with careful checks to ensure the model works well across centers. They will also use causal methods to understand how AI-guided decisions might have changed actual implantation outcomes in past cases. If the initial phase is successful, a multicenter randomized trial will compare AI-guided embryo selection to standard methods to see if it improves pregnancy results.
Why it matters
Potential benefit: If successful, the platform could standardize embryo assessment, reduce variability, and improve IVF implantation and pregnancy rates.
How similar studies have gone: Previous AI-assisted embryo assessment work shows promise, but this project seeks prospective validation and randomized comparison.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Hajirasouliha, Iman — Weill Medical Coll of Cornell Univ
- Study coordinator: Hajirasouliha, Iman
Related research
Other NIH-funded projects on the same topics.
-
Destruction of noncoding RNAs in cancer
This grant funds research to understand how noncoding RNAs are broken down, which could reveal new ways to influence cancer development and progression.
-
Coaching and Navigation by Community Health Workers via Telehealth for High-Risk Hypertension
A program using telehealth and community health workers to help adults with severe hypertension connect to primary care and follow practical, heart-healthy lifestyle tips.
-
Corticospinal neurons and recovery of precise forelimb movement after spinal cord injury
This project studies how spine injuries change brain circuits and whether targeted rehabilitation helps restore precise forelimb movement.
-
Thiamine-boosting therapy for Alzheimer’s: understanding how benfotiamine may reduce harmful AGE in DP patients
A medication-based approach using high-dose vitamin B1 (benfotiamine) is studied to help people with Alzheimer's by reducing harmful sugar-related molecules.
-
Turning APOE4 into protective APOE2 or APOE3Christchurch to help with Alzheimer’s
A patient-facing explanation of a treatment idea that aims to change a genetic risk factor for Alzheimer's disease in the brain.
-
ROMA:Women — comparing single vs multiple arterial grafts in women undergoing CABG
A women-focused clinical trial tests whether using more arterial grafts during heart bypass surgery improves outcomes and quality of life for women.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.