Ageotypes: Mapping How We Age Over a Lifetime
Official title: Project 1: Ageotypes
Funded at Arizona State University-Tempe Campus · NIH-11435945 · Data updated 2026-11-12
Aimed at understanding how aging patterns develop across people and primates to reveal when aging speeds up or slows down and what predicts healthier longevity.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,399,958 |
| NIH project number | 1U19AG092410-01A1 |
| Project ID | NIH-11435945 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older who may be candidates for future age-related health interventions or participation in related translational studies.
✕Less likely to help
The study itself is observational in animals and humans; individual patients may not directly benefit unless involved in future trials derived from these findings.
What this research studies
This project studies aging patterns across molecular, physiological, physical, and social aspects in both humans and a nonhuman primate model. It uses a systems biology approach to identify distinct age-related profiles called ageotypes and agingtypes. By following many individuals over time and comparing macaques with human data, it seeks to pinpoint when aging accelerates and which factors best predict reproductive aging and mortality. Findings could highlight windows for intervention to extend healthspan. Researchers will translate findings from rhesus macaques to mice and humans to strengthen relevance for people.
Why it matters
Potential benefit: If successful, the work could identify targets and timing for interventions aimed at extending healthy years.
How similar studies have gone: Previous multi-domain aging studies in primates and humans have shown promise linking aging patterns to health outcomes, supporting the potential for impactful translational insights.
Where this research is happening
-
Arizona State University-Tempe Campus
Scottsdale, United States Active
Researchers
- Principal investigator: Higham, James P — Arizona State University-Tempe Campus
- Study coordinator: Higham, James P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.