Advanced Multiplexed UPLC-MS/MS System to Profile Metabolites
Official title: Advanced Multiplexed UPLC-MS/MS System for Target Metabolomics
Funded at University of Washington · NIH-11338680 · Data updated 2026-11-12
A grant to upgrade and expand a high-throughput metabolomics platform that measures hundreds of metabolites, helping researchers understand metabolic differences in patients with diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 15, 2026 |
| Project end | July 14, 2027 |
| Funding year | 2026 |
| Award (this year) | $680,391 |
| NIH project number | 1S10OD040220-01 |
| Project ID | NIH-11338680 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for future benefit include patients whose conditions involve metabolic dysregulation and who may contribute samples to related metabolomics studies or future trials.
✕Less likely to help
Patients not involved in metabolic profiling research or not linked to metabolomics-related studies may see no direct benefit.
What this research studies
The Northwest Metabolomics Research Center at the University of Washington has built a robust, reproducible metabolomics platform capable of measuring over 370 aqueous metabolites. This S10 funding will expand capacity and add reversed-phase chromatography to increase metabolite coverage, addressing current demand and sample backlogs. The enhanced system will support both basic and clinical researchers studying diseases by providing more comprehensive metabolic profiling from patient samples. Researchers aim to maintain high-quality measurements and enable timely processing of thousands of biological samples in collaboration with numerous investigators.
Why it matters
Potential benefit: If successful, patients could benefit from faster, more comprehensive metabolic analyses that inform disease understanding and potential avenues for diagnosis or treatment personalization.
How similar studies have gone: The platform has already generated 37 peer-reviewed articles and analyzed over 14,000 samples across 60+ collaborators, indicating a track record of success.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Raftery, Daniel — University of Washington
- Study coordinator: Raftery, Daniel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.