Advanced multi-omic cancer profiling center
Official title: Center for Advanced Multi-Omic Characterization of Cancer
Funded at Battelle Pacific Northwest Laboratories · NIH-11323966 · Data updated 2026-11-12
A research center aims to deeply profile human tumors using multiple omics to better understand cancer and connect molecular findings with patient outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | June 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,240,013 |
| NIH project number | 5U24CA271012-05 |
| Project ID | NIH-11323966 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients whose tumor samples are collected and contributed to CPTAC/CPTAC-related studies may indirectly benefit from improved cancer understanding and future diagnostic advances.
✕Less likely to help
Direct patient benefit is not guaranteed; the grant primarily advances cancer biology and biomarker discovery.
What this research studies
This center plans to systematically characterize tumor samples from the National Cancer Institute and integrate proteomics, genomics, metabolomics, and other data to reveal how cancers differ at the molecular level. By adding acetylome and ubiquitinome analyses alongside phosphoproteomics, plus spatial and single-cell approaches, the project seeks a richer view of protein interactions, degradation, and signaling in cancer. The work continues CPTAC’s mission to provide high-quality, comprehensive data that can inform future diagnostics and treatments. Results should help clinicians and researchers identify new biomarkers and therapeutic targets.
Why it matters
Potential benefit: If successful, patients could benefit from improved cancer biomarkers and more precise targets for therapy.
How similar studies have gone: CPTAC has demonstrated success in comprehensive proteogenomic cancer profiling and data integration over the past decade.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Liu, Tao — Battelle Pacific Northwest Laboratories
- Study coordinator: Liu, Tao
Related research
Other NIH-funded projects on the same topics.
-
Proteomics Center for MoTrPAC to map exercise effects in human tissues
A research center is studying how physical activity changes proteins and their modifications in muscles and fat to understand exercise benefits for chronic diseases.
-
Islet cell pathways and regulators in early type 1 diabetes
Researchers will study how insulin-producing beta cells deteriorate before type 1 diabetes becomes clinically apparent, using cutting-edge tissue analysis to find molecular clues that could lead to new therapies.
-
Protein targets of nitazenes and their metabolites in human cells
Researchers will map which human brain, heart, and lung proteins interact with nitazene opioids, helping explain why these drugs can be so potent and dangerous.
-
High-throughput multiomic profiling of single cells
A new platform will measure proteins, RNAs, and metabolites in thousands of individual human cells to better understand how cells regulate themselves.
-
Single-cell phospho-proteomics to map breast tumor microenvironment
A researcher will develop a new, highly sensitive single-cell proteomics tool to map proteins and phosphorylation in breast cancer tumor environments, helping doctors tailor treatments.
-
High-Throughput Lipid Profiling with Precise Structures for Phenotypic Screening
A project to develop advanced lipid profiling that can precisely identify lipid structures to help understand and screen diseases like Alzheimer's.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.