Proteomics Center for MoTrPAC to map exercise effects in human tissues
Official title: ProMoTr: A Proteomics Center for MoTrPAC
Funded at Battelle Pacific Northwest Laboratories · NIH-11516019 · Data updated 2026-11-12
A research center is studying how physical activity changes proteins and their modifications in muscles and fat to understand exercise benefits for chronic diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | December 8, 2016 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $530,000 |
| NIH project number | 3U24DK112349-08S1 |
| Project ID | NIH-11516019 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with chronic diseases who participate in exercise studies and provide tissue samples (muscle and fat) or participate in related MoTrPAC activities.
✕Less likely to help
Individuals not participating in MoTrPAC or those without access to muscle or adipose tissue sampling would not directly benefit from this specific project.
What this research studies
This project supports scientists in analyzing proteins and their modifications in human tissues collected from participants in MoTrPAC to build a molecular map of how exercise affects the body. It uses advanced protein profiling and data sharing to understand signaling pathways that respond to physical activity. The work focuses on skeletal muscle and subcutaneous fat to capture key signals involved in exercise adaptations and chronic disease mitigation. Findings could help personalize exercise plans and identify new biomarkers of beneficial responses. This program emphasizes collaboration, data integration, and high-quality proteomics analyses across sites.
Why it matters
Potential benefit: If successful, patients may benefit from clearer molecular targets to optimize exercise plans and monitor responses.
How similar studies have gone: Previous proteomics studies in exercise research have advanced understanding, and this project builds on established multi-omics approaches within MoTrPAC.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Adkins, Joshua N. — Battelle Pacific Northwest Laboratories
- Study coordinator: Adkins, Joshua N.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.