Administrative Core of a Center for Spatiotemporal Tumor Analytics
Official title: Administrative Core
Funded at Institute for Systems Biology · NIH-11415802 · Data updated 2026-11-12
A coordinated center is building advanced tools and collaborations to study how to best sequence immunotherapy and targeted therapies for solid tumors like metastatic melanoma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Institute for Systems Biology NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 22, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $416,281 |
| NIH project number | 5U54CA274509-05 |
| Project ID | NIH-11415802 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with solid tumors, starting with metastatic cutaneous melanoma, who could participate in research using tumor tissues or related clinical studies.
✕Less likely to help
Some patients may not directly benefit if the research path does not lead to immediate clinical options for their cancer type or stage.
What this research studies
This grant supports an administrative core that coordinates researchers across ISB, Yale, and UCLA, along with outreach, pilot projects, and cross-consortium efforts. The center aims to bring together clinicians, biologists, engineers, and computational scientists to advance multiomic profiling, animal models, and tumor tissue biorepositories. The focus is on enabling rapid collaboration and timely progress toward clinic-ready strategies for sequential immunotherapy and targeted therapies in cancer. The program emphasizes cross-disciplinary teamwork, resource sharing, and proactive problem-solving to overcome scientific and logistical challenges.
Why it matters
Potential benefit: If successful, patients with advanced cancers could benefit from faster development of effective immunotherapy sequences and combination strategies.
How similar studies have gone: Previous multi-institution collaborations with integrated data and tissue resources have accelerated translational cancer research, supporting the potential for similar success here.
Where this research is happening
-
Institute for Systems Biology
Seattle, United States Active
Researchers
- Principal investigator: Heath, James R. — Institute for Systems Biology
- Study coordinator: Heath, James R.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.