Adaptive decision support to improve opioid treatment in ED care
Official title: ADAPT: Adaptive Decision support for Addiction Treatment
Funded at Yale University · NIH-11378360 · Data updated 2026-11-12
A flexible, computer-based tool helps emergency departments start evidence-based buprenorphine treatment for people with opioid use disorder.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 30, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,183,096 |
| NIH project number | 5R33DA059884-04 |
| Project ID | NIH-11378360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with opioid use disorder who present to emergency departments or similar acute care settings.
✕Less likely to help
Patients without opioid use disorder or those not receiving ED care for OUD may not benefit.
What this research studies
This project develops and tests an electronic health record–based decision support system that guides clinicians in initiating buprenorphine for patients with opioid use disorder during routine ED visits. Building on prior work, the team aims to rapidly adapt CDS tools as new evidence emerges and spread them across healthcare systems. The approach focuses on real-time workflows and practical implementation to make evidence-based care faster and more consistent for patients in acute care settings.
Why it matters
Potential benefit: If successful, it could increase timely access to buprenorphine in emergency departments and improve initiation rates for people with opioid use disorder.
How similar studies have gone: Prior CDS interventions increased buprenorphine initiation, and ongoing adaptation aims to broaden reach across systems.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Melnick, Edward Robert — Yale University
- Study coordinator: Melnick, Edward Robert
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.