Adaptive computer practice to improve word-finding in aphasia

Integrating complementary learning principles in aphasia rehabilitation via adaptive modeling

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11260184

This project uses computer programs that change practice difficulty to help people with aphasia find words more easily and keep those gains over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11260184 on NIH RePORTER

What this research studies

You would use a computer-based naming program that automatically adjusts how hard tasks are so you are challenged but not overwhelmed. The team will run two parallel clinical trials comparing different adaptive models that blend common therapy ideas like errorless versus effortful practice and massed versus spaced practice. The goal is to keep a “desirable difficulty” during practice so learned words stick and carry over into everyday speaking. Treatment will include repeated naming practice with the program tailoring trials to your performance and periodic in-person assessments.

Who could benefit from this research

Good fit: Ideal candidates are adults with aphasia after stroke or other acquired brain injury who have word-finding (anomia) difficulties and can participate in computer-based therapy and clinic visits.

Not a fit: People without significant word-finding problems, those with severe global language impairment who cannot use the computer tasks, or those with rapidly progressive neurodegenerative aphasias may not benefit from this program.

Why it matters

Potential benefit: If successful, this approach could give people with aphasia longer-lasting improvements in word-finding that transfer to natural conversation.

How similar studies have performed: Prior work supports spaced practice and retrieval-based naming therapy for aphasia, but using adaptive model-based algorithms to continuously balance learning strategies is a novel application.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.