A tool to help decide kidney transplants for people who had cancer
Official title: A clinical decision support tool to understand the survival benefit of kidney transplantation in candidates with a history of cancer
Funded at Hennepin Healthcare Research Institute · NIH-11381076 · Data updated 2026-11-12
A patient-friendly tool will help doctors and patients understand how kidney transplant may affect survival for people with end-stage kidney disease who have a history of cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hennepin Healthcare Research Institute NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 5, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $336,491 |
| NIH project number | 5R01DK140270-03 |
| Project ID | NIH-11381076 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with end-stage kidney disease and a history of cancer who are being evaluated for kidney transplantation.
✕Less likely to help
Patients without a history of cancer or those not being considered for transplantation may not directly benefit from this tool.
What this research studies
This project develops a decision-support tool to estimate survival benefits of kidney transplantation versus remaining on dialysis for patients with both end-stage kidney disease and a history of cancer. It uses existing data to improve predictions about pre- and post-transplant outcomes so clinicians can discuss options with patients who are in cancer remission. The goal is to reduce uncertainty and support personalized, timely transplant decisions in a context of organ shortages. If successful, the tool could help more patients make informed choices and potentially improve survival and quality of life. The work is led by Hennepin Healthcare Research Institute in Minneapolis, focusing on adults with cancer history considering transplantation.
Why it matters
Potential benefit: If successful, patients with ESKD and cancer history could receive clearer guidance on whether transplant offers a survival advantage.
How similar studies have gone: Prior data suggest clinical decision support tools can improve transplant planning, but this area remains needed for cancer history in ESKD.
Where this research is happening
-
Hennepin Healthcare Research Institute
Minneapolis, United States Active
Researchers
- Principal investigator: Hart, Allyson — Hennepin Healthcare Research Institute
- Study coordinator: Hart, Allyson
Related research
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-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.