A Smart Pill for Collecting Gut Samples
Ingestible Pill for spatially targeted sampling of gut microbiome
This project is creating a tiny, swallowable pill that can collect samples from specific areas of your digestive system without needing invasive procedures.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Medford NIH-funded |
| Lab location | 1 site (Boston, UNITED STATES) |
| Project ID | NIH-11167641 on NIH RePORTER |
What this research studies
We are developing a new type of ingestible pill, called a "micro-pill," designed to collect samples from precise locations within your gastrointestinal (GI) tract. This pill will use tiny sensors to detect changes in pH and oxygen levels as it travels, allowing it to know its exact position and collect samples autonomously. This innovative approach aims to replace current methods that often require more invasive procedures to get these important samples. The pill will be powered by a small battery and can even be activated wirelessly if needed.
Who could benefit from this research
Good fit: This research is focused on developing a device for adults aged 21 and older who may need targeted sampling of their gut microbiome.
Not a fit: Patients who do not require specific sampling of their gut or those with conditions that significantly alter GI tract pH/pO2 in unpredictable ways may not directly benefit from this particular device.
Why it matters
Potential benefit: If successful, this technology could offer a much less invasive and more comfortable way to collect valuable information about your gut health, potentially leading to better diagnosis and treatment of digestive conditions.
How similar studies have performed: The researchers have experimented with an earlier version of this pill, and this project builds upon that work with an innovative new control mechanism for precise sampling.
Where this research is happening
Boston, UNITED STATES
- Tufts University Medford — Boston, United States (Active)
Researchers
- Principal investigator: Sonkusale, Sameer R — Tufts University Medford
- Study coordinator: Sonkusale, Sameer R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.