NIH-funded research R21 grant

A practical, online program to reduce loneliness and improve mental health for older adults living with HIV

Official title: Feasibility study of an integrated intervention for social isolation and mental health among older adults living with HIV

Funded at University of California, San Diego · NIH-11407223 · Data updated 2026-11-12

A small, online program helps older adults with HIV stay connected and healthier by combining social activities with a simple mental-health support approach.

More Mental Health research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 9, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$210,510
NIH project number1R21AG102097-01
Project IDNIH-11407223 on NIH RePORTER

Who could benefit from this research

Could help

Older adults aged 50+ who are living with HIV and are willing to participate in a 10-week online program.

Less likely to help

People not living with HIV or under 50 may not experience direct benefits from this program.

What this research studies

This project tests a web-based program called VV+ that blends a social engagement platform with a brief, therapist-guided mental health tool for people aged 50 and up living with HIV. Over 10 weeks, 80 participants will be randomly assigned to VV+ or a healthy aging control to see if the program is doable and well-liked, and to gather early signals of benefit. Researchers will measure how easy it is to recruit and keep participants, how often people use the program, and feedback on what works and what could be improved. The study builds on prior community input and aims to reduce loneliness, expand social networks, and improve mood and well-being. If feasible and acceptable, VV+ could inform future larger trials to support aging individuals with HIV.

Why it matters

Potential benefit: If successful, VV+ could help reduce loneliness and improve mental health and social engagement for older adults living with HIV.

How similar studies have gone: Previous work supports using digital social and mental-health tools to improve well-being in older adults, with mixed but promising results.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Nguyen, Annie Lu — University of California, San Diego
  • Study coordinator: Nguyen, Annie Lu

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.