NIH-funded research R01 grant

Maternal mental health help to protect kids’ breathing health

Official title: Promoting child respiratory health through novel psychosocial targets: An investigation of a maternal mental health intervention

Funded at Univ of North Carolina Chapel Hill · NIH-11614750 · Data updated 2026-11-12

A mother-focused mental health program is tested to see if improving moms’ mood can also support better breathing and fewer asthma symptoms in children.

More Mental Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 15, 2025
Project endJune 30, 2029
Funding year2026
Award (this year)$155,058
NIH project number3R01HL180944-02S1
Project IDNIH-11614750 on NIH RePORTER

Who could benefit from this research

Could help

Children aged from birth to early adolescence whose mothers participate in the maternal depression intervention and who are part of the Bachpan birth cohort in rural Pakistan.

Less likely to help

Children whose mothers do not participate in the intervention or who experience unrelated factors affecting respiratory health may not benefit.

What this research studies

This project builds on a birth-cohort study in rural Pakistan and adds a randomized maternal depression intervention to see if improving maternal mental health leads to better child lung function. Researchers will track children from pregnancy through early adolescence to observe respiratory outcomes and adverse experiences that might influence breathing. The study uses existing cohort infrastructure, with careful attention to long-term follow-up and data collection in a low-resource setting. If successful, the approach could point to a scalable way to improve child respiratory health by supporting mothers. The work involves collaboration across disciplines to translate maternal mental health care into potential respiratory benefits for children.

Why it matters

Potential benefit: If the maternal intervention improves child respiratory health, families could experience fewer asthma symptoms and better long-term lung function.

How similar studies have gone: Prior work suggests maternal well-being can influence child health, but this specific randomized approach to respiratory outcomes is novel.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Frost, Allison — Univ of North Carolina Chapel Hill
  • Study coordinator: Frost, Allison

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.