A new system for advanced tissue imaging
Official title: Orion: A novel platform for rapid multiplexed tissue imaging
Funded at Brigham and Women's Hospital · NIH-10853757 · Data updated 2026-11-12
This study is testing a new imaging system that helps doctors and researchers see different types of cells in tissue samples more clearly and quickly, which can help them better understand complex diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $600,000 |
| NIH project number | 1S10OD034446-01A1 |
| Project ID | NIH-10853757 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with complex tissue-related diseases, such as cancers or autoimmune disorders, where detailed cellular analysis is critical.
✕Less likely to help
Patients with conditions that do not require detailed tissue imaging or those who are not undergoing tissue analysis may not benefit from this research.
What this research studies
This research focuses on acquiring a cutting-edge imaging system that allows for rapid and detailed visualization of multiple cell types in tissue samples. By using advanced immunofluorescence techniques, the system can identify and analyze various cell interactions simultaneously, which is crucial for understanding complex diseases. The approach minimizes the degradation of samples and enhances the accuracy of imaging through the use of multiple fluorescent markers. This technology aims to improve the efficiency and effectiveness of tissue analysis in clinical and research settings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better understanding of diseases, ultimately improving patient care.
How similar studies have gone: Other research has shown success with advanced imaging techniques, indicating that this approach has the potential to significantly enhance tissue analysis.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Santagata, Sandro — Brigham and Women's Hospital
- Study coordinator: Santagata, Sandro
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.