A new method to screen alcohol's effects using brain-like tissues.
Official title: A high throughput alcohol screening platform (HT-ASP) incorporating cortical organoids.
Funded at Cfd Research Corporation · NIH-11072376 · Data updated 2026-11-12
This study is exploring how alcohol affects the brain by using tiny, lab-grown brain models, which could help us find better treatments for people struggling with alcohol use.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cfd Research Corporation NIH-funded |
| Lab location | 1 site (Huntsville, United States) |
| Project start | May 15, 2025 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $499,987 |
| NIH project number | 1R43AA032150-01 |
| Project ID | NIH-11072376 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of alcohol use disorder or those affected by alcohol-related brain changes.
✕Less likely to help
Patients who do not have a history of alcohol use or related brain conditions may not benefit from this research.
What this research studies
This research develops a high throughput screening platform that utilizes 3D brain organoids to study the effects of alcohol on brain function. By creating these organoids from stem cells, researchers can mimic the human brain's response to alcohol exposure in a controlled laboratory setting. The goal is to better understand how alcohol impacts different brain regions, which could lead to improved treatments for alcohol use disorder. Patients may benefit from insights gained through this innovative approach to drug screening.
Why it matters
Potential benefit: If successful, this research could lead to more effective therapies for individuals struggling with alcohol use disorder.
How similar studies have gone: Other research has shown promise in using organoid models for drug screening, indicating potential success for this novel approach.
Where this research is happening
-
Cfd Research Corporation
Huntsville, United States Active
Researchers
- Principal investigator: Roehm, Kevin — Cfd Research Corporation
- Study coordinator: Roehm, Kevin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.