Developing a new antibiotic to treat drug-resistant gonorrhea
A Novel Mechanism of Action Natural Product for Treatment of Drug-Resistant Gonorrhea
['FUNDING_SBIR_1'] · CFD RESEARCH CORPORATION · NIH-11076691
This study is working on a new antibiotic to help fight gonorrhea, especially the tough strains that don't respond to current treatments, using a special natural product that has shown promise in the lab.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CFD RESEARCH CORPORATION (nih funded) |
| Locations | 1 site (HUNTSVILLE, UNITED STATES) |
| Trial ID | NIH-11076691 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new class of antibiotics specifically targeting Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, which has become increasingly resistant to existing treatments. The project will utilize a novel natural product that has shown potent activity against this bacteria. Researchers will optimize this natural product to enhance its effectiveness and safety, followed by testing its efficacy in a mouse model of gonorrhea infection. The ultimate goal is to develop a new antibiotic that can effectively combat drug-resistant strains of gonorrhea.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with gonorrhea, particularly those with infections resistant to current antibiotic treatments.
Not a fit: Patients with non-gonococcal infections or those who do not have drug-resistant gonorrhea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment option for patients suffering from drug-resistant gonorrhea.
How similar studies have performed: While antibiotic resistance is a significant challenge, this approach utilizing a novel natural product is relatively new and has not been extensively tested in similar contexts.
Where this research is happening
HUNTSVILLE, UNITED STATES
- CFD RESEARCH CORPORATION — HUNTSVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINGHAL, AJ — CFD RESEARCH CORPORATION
- Study coordinator: SINGHAL, AJ
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.