Developing viruses to treat infections caused by mycobacteria.
Official title: SBIR Topic 131: Development of Bacteriophage for Treatment of Mycobacterial Infections
Funded at Cfd Research Corporation · NIH-11203283 · Data updated 2026-11-12
This study is exploring a new treatment using special viruses that can help fight tough infections caused by mycobacteria, especially for people who haven't had success with regular antibiotics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cfd Research Corporation NIH-funded |
| Lab location | 1 site (Huntsville, United States) |
| Project start | September 10, 2024 |
| Project end | September 9, 2025 |
| Funding year | 2024 |
| Award (this year) | $297,740 |
| NIH project number | 75N93024C00060-0-9999-1 |
| Project ID | NIH-11203283 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with mycobacterial infections, particularly those who have not responded well to standard antibiotic treatments.
✕Less likely to help
Patients with infections caused by bacteria other than mycobacteria may not benefit from this research.
What this research studies
This research focuses on creating therapeutic products using bacteriophages, which are viruses that specifically target and kill mycobacteria, including those that are resistant to antibiotics. The approach involves preclinical development, meaning that the research is in the early stages before it can be tested in humans. By targeting non-tuberculous mycobacterial (NTM) infections, this research aims to provide an alternative treatment option for patients who have limited responses to traditional antibiotics. The methodology includes rigorous testing of these phage products to ensure their effectiveness and safety.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option for patients suffering from antibiotic-resistant mycobacterial infections.
How similar studies have gone: Other research has shown promise in using bacteriophages to treat bacterial infections, indicating that this approach could be effective for mycobacterial infections as well.
Where this research is happening
-
Cfd Research Corporation
Huntsville, United States Active
Researchers
- Principal investigator: Bhatt, Ketan — Cfd Research Corporation
- Study coordinator: Bhatt, Ketan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.