Controlled-release eczema bandage
Official title: Controlled Release Eczema Bandage (CREB)
Funded at Cfd Research Corporation · NIH-11195587 · Data updated 2026-11-12
A soft bandage that slowly releases a natural, microbiome-friendly compound to calm eczema flare-ups in children and adults.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cfd Research Corporation NIH-funded |
| Lab location | 1 site (Huntsville, United States) |
| Project start | August 1, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $920,285 |
| NIH project number | 5R44AT011486-03 |
| Project ID | NIH-11195587 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with atopic dermatitis (eczema), including children and adults who experience flare-ups, would be the intended candidates for this approach.
✕Less likely to help
People with non-atopic skin rashes, different dermatologic diagnoses, or known allergies to the bandage materials are unlikely to benefit from this specific therapy.
What this research studies
You would be hearing about a wet-wrap bandage that slowly releases a natural compound designed to soothe the immune response in atopic dermatitis and target Staphylococcus aureus while sparing helpful skin bacteria. The compound is embedded into cellulose-based fabrics such as rayon and cotton to give controlled, sustained release against inflamed skin. The current work tests these bandages in mouse models of eczema to look at skin healing and the effects on the skin microbiome. If those results are promising, the approach could move toward human testing and clinical use to reduce reliance on steroid creams.
Why it matters
Potential benefit: If successful, this could calm eczema flares while protecting the skin microbiome and potentially reduce or replace the need for steroid ointments.
How similar studies have gone: Topical microbiome therapies and wet-wraps have shown promise in prior work, but a controlled-release microbiome-balancing bandage is a novel approach that has not yet been widely tested in humans.
Where this research is happening
-
Cfd Research Corporation
Huntsville, United States Active
Researchers
- Principal investigator: Singhal, Aj — Cfd Research Corporation
- Study coordinator: Singhal, Aj
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.