A new method for screening liver diseases using multiple miRNA markers
Official title: A novel and inexpensive multiplex miRNA platform for liver diseases screening
Funded at Kasa Bio, L.l.c. · NIH-10821132 · Data updated 2026-11-12
This study is working on a new, affordable way to quickly check for several tiny molecules in your body that can help spot liver diseases linked to alcohol use and diabetes, making it easier for doctors to catch these issues early and keep track of your health.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kasa Bio, L.l.c. NIH-funded |
| Lab location | 1 site (Peachtree Corners, UNITED STATES) |
| Project start | June 1, 2024 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $273,974 |
| NIH project number | 1R43AA031448-01 |
| Project ID | NIH-10821132 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for liver diseases, particularly those with a history of alcohol use or type 2 diabetes.
✕Less likely to help
Patients with liver diseases unrelated to alcohol consumption or diabetes may not benefit from this research.
What this research studies
This research focuses on developing a novel and cost-effective platform for detecting multiple microRNAs (miRNAs) associated with liver diseases, particularly those related to alcohol consumption and diabetes. By utilizing a unique Zip-Melt Multiplex miRNA Solution, the study aims to improve the efficiency of miRNA detection, allowing for simultaneous analysis of multiple biomarkers from various sample types, such as tissue or body fluids. This approach seeks to enhance early detection and monitoring of liver diseases, which are significant contributors to global morbidity and mortality.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnosis of liver diseases, improving patient outcomes and treatment options.
How similar studies have gone: While the approach of multiplex miRNA detection is innovative, similar methodologies in oncology have shown promise, indicating potential for success in this area as well.
Where this research is happening
-
Kasa Bio, L.l.c.
Peachtree Corners, United States Active
Researchers
- Principal investigator: Bala, Shashi — Kasa Bio, L.l.c.
- Study coordinator: Bala, Shashi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.