Condition
Wrinkle clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Wrinkle clinical trials that are recruiting, at sites in 3 countries (most in United States (2), Italy (2), Netherlands (1)). By phase: Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 3Countries
Newest Wrinkle clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| INNEA and INNEA AQUA injections for cheek and décolletage wrinkles | — | Brescia, Brescia and 2 other locations | Recruiting | Jan 9, 2026 |
| Treatment for various skin conditions using AVAVA technology | — | Waltham, Massachusetts | Recruiting | Mar 11, 2025 |
| Head-to-Head Comparison of BoNT-A Treatments for Glabellar Lines | Phase 4 | Amsterdam and 2 other locations | Recruiting | Jun 7, 2024 |
| Hyaluronic acid plus recombinant collagen volumizing filler for facial wrinkles and sagging | — | Roma | Recruiting | Mar 28, 2024 |
| Micro-coring device treatment for moderate to severe cheek wrinkles | — | Sacramento, California and 5 other locations | Recruiting | Jan 4, 2019 |
All recruiting trials (5)
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INNEA and INNEA AQUA injections for cheek and décolletage wrinkles
This will test whether INNEA and INNEA AQUA injections reduce cheek and décolletage wrinkles in women aged 35–65.
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Treatment for various skin conditions using AVAVA technology
This study is testing a new device called AVAVA to see if it can help improve skin problems like acne, scars, and wrinkles.
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Head-to-Head Comparison of BoNT-A Treatments for Glabellar Lines
A multicenter, triple-blind study will test all FDA-approved Botulinum Neurotoxin Type A products to see which best reduces glabellar frown lines and lasts the longest.
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Hyaluronic acid plus recombinant collagen volumizing filler for facial wrinkles and sagging
This trial will try a hyaluronic acid and recombinant collagen filler to reduce facial wrinkles, scars, and tissue laxity in non-smoking adults aged 18–70.
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Micro-coring device treatment for moderate to severe cheek wrinkles
This study will try a micro-coring device to reduce moderate to severe cheek wrinkles in adults ages 40 to 70.
Related topics
Quick answers
How many Wrinkle clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), Italy (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.