Condition

Uncontrolled Hypertension clinical trials and research

• 11Clinical trials
• 1NIH research projects
• 4Countries

Newest Uncontrolled Hypertension clinical trials

All recruiting trials (11)

• Baxdrostat for Uncontrolled Hypertension in Chinese Adults

  This study tests whether baxdrostat 2 mg once daily can lower 24-hour systolic blood pressure in adults with uncontrolled hypertension who are already on multiple hypertension medications.

  Recruiting Phase 3 AstraZeneca · Beijing and 50 other locations · NCT07686120

• SAL0140 at different doses for uncontrolled hypertension

  This trial tests whether SAL0140 at various doses can help people with uncontrolled high blood pressure compared to placebo.

  Recruiting Phase 2 Shenzhen Salubris Pharmaceuticals Co., Ltd. · Beijing, Beijing Municipality · NCT07654140

• Modified-release RTN-001 for adults with uncontrolled high blood pressure

  This trial will test whether taking a daily modified-release RTN-001 capsule lowers blood pressure in adults whose hypertension remains uncontrolled despite at least two blood-pressure medicines.

  Recruiting at 43 sites Phase 2 Retension Pharmaceuticals. Inc. · Alexander City, Alabama and 43 other locations · NCT07142356

• Iloperidone for adults with uncontrolled high blood pressure

  We are testing whether iloperidone can lower blood pressure in adults whose blood pressure stays high despite at least 8 weeks of one or more blood pressure medications.

  Recruiting at 18 sites Phase 2 Vanda Pharmaceuticals · Phoenix, Arizona and 27 other locations · NCT07090161

• SAL0140 safety and dosing in healthy Chinese adults

  This project will test whether SAL0140 is safe, well tolerated, and how it is processed by the body in healthy Chinese adults to guide dosing for uncontrolled hypertension.

  Recruiting Phase 1 Shenzhen Salubris Pharmaceuticals Co., Ltd. · Guangzhou, Guangdong · NCT07051603

• Adaptive program to reduce food insecurity for people with uncontrolled high blood pressure

  This study will test whether different food-support approaches—resource information, community health worker help, or medically-tailored meals—help adults with uncontrolled hypertension who face food insecurity stick to diet and medication plans and lower their blood pressure.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT07031739

• Renal pelvic denervation for adults with uncontrolled high blood pressure

  This trial will test whether delivering radiofrequency energy to the renal pelvis can lower blood pressure in adults whose hypertension remains uncontrolled on two medications.

  Recruiting at 8 sites Verve Medical, Inc · Birmingham, Alabama and 8 other locations · NCT07005050

• Improving medication adherence in patients with uncontrolled hypertension using urine tests

  This study is testing if using urine tests can help people with uncontrolled high blood pressure stick to their medication better and improve their health.

  Recruiting Changi General Hospital · Singapore · NCT06938633

• 24-hour wearable blood pressure monitoring comparison

  We will test if wearable cuffless and cuff-based devices can reliably measure blood pressure over 24 hours compared with a standard ambulatory cuff monitor in adults with normal or high blood pressure.

  Recruiting Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT06610448

• Managing high blood pressure in Black patients remotely

  This study tests whether managing high blood pressure at home with help from a pharmacist and a community health worker works better than regular clinic care for Black patients with uncontrolled hypertension.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT06527794

• Improving blood pressure management in patients with chronic kidney disease

  This study tests if a stronger approach to lowering blood pressure using diuretics can help people with chronic kidney disease and high blood pressure feel better and stay healthier.

  Recruiting at 37 sites Phase 3 University Hospital, Tours · Angers and 39 other locations · NCT05732727

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Using electronic health records to improve care for patients with high blood pressure

  This study is looking to help black adults with high blood pressure by using special tools to give personalized treatment advice and improve communication with their doctors, making it easier for them to manage their health and get better care.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10758532

Related topics

Quick answers

How many Uncontrolled Hypertension clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (6 trials), China (3 trials), Singapore (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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