Managing high blood pressure in Black patients remotely

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares two methods for managing uncontrolled hypertension in Black patients. One method involves home blood pressure telemonitoring with support from a pharmacist and a community health worker, while the other method provides enhanced usual clinic-based care along with a home blood pressure monitor. The trial aims to evaluate the effectiveness of these approaches in improving blood pressure control. It is designed as a pragmatic effectiveness-implementation hybrid trial with two distinct study arms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Black or African American race
* Hypertension diagnosis
* aged 21 to 85 years
* Uncontrolled blood pressure as defined by \[a\] most recent SBP ≥140 mmHg and an additional SBP≥140 mmHg within the past 12 months in an outpatient setting (excluding urgent care, emergency department or surgery clinic), or \[b\] most recent SBP\>160mmHg in an outpatient setting (excluding urgent care, emergency department or surgery clinic), or \[c\] referral by PCP for uncontrolled hypertension with at least one documented SBP≥140 mmHg (in clinic or at home) in the past 12 months; and (v) primary care provided at a participating clinic.
* Able to speak English
* Primary care provided at a participating clinic

Exclusion Criteria:

* currently pregnant or planning to get pregnant during the study period
* residence in a long-term care facility, hospice or with a terminal illness with less than 1 year life expectancy as determined by the Primary Care Physician or study team. Stable chronic illness such as compensated cirrhosis, chronic obstructive pulmonary disease, congestive heart failure etc. will not be excluded.
* estimated Glomerular Filtration Rate (eGFR) \<30 ml/min or on dialysis. Patients with a functioning kidney transplant will not be excluded.
* inability to provide informed consent or participate in study procedures. For example, conditions that limit ability to participate in phone visits or check BPs in at least one arm.
* currently participating in another BP management program.
* plan to move out of the area within the next 12 months.
* Hispanic ethnicity.

Where it's running

• Wake Forest University Health Sciences
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Yhenneko J. Taylor, PhD — Wake Forest University Health Sciences
• Study coordinator: Yhenneko J. Taylor, PhD
• Email: Yhenneko.Taylor@advocatehealth.org
• Phone: (704) 355-6562

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Baxdrostat for Uncontrolled Hypertension in Chinese Adults

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• SAL0140 at different doses for uncontrolled hypertension

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• Modified-release RTN-001 for adults with uncontrolled high blood pressure

  This trial will test whether taking a daily modified-release RTN-001 capsule lowers blood pressure in adults whose hypertension remains uncontrolled despite at least two blood-pressure medicines.

  Recruiting at 43 sites Phase 2 Retension Pharmaceuticals. Inc. · Alexander City, Alabama and 43 other locations · NCT07142356

• Iloperidone for adults with uncontrolled high blood pressure

  We are testing whether iloperidone can lower blood pressure in adults whose blood pressure stays high despite at least 8 weeks of one or more blood pressure medications.

  Recruiting at 18 sites Phase 2 Vanda Pharmaceuticals · Phoenix, Arizona and 27 other locations · NCT07090161

• SAL0140 safety and dosing in healthy Chinese adults

  This project will test whether SAL0140 is safe, well tolerated, and how it is processed by the body in healthy Chinese adults to guide dosing for uncontrolled hypertension.

  Recruiting Phase 1 Shenzhen Salubris Pharmaceuticals Co., Ltd. · Guangzhou, Guangdong · NCT07051603

• Adaptive program to reduce food insecurity for people with uncontrolled high blood pressure

  This study will test whether different food-support approaches—resource information, community health worker help, or medically-tailored meals—help adults with uncontrolled hypertension who face food insecurity stick to diet and medication plans and lower their blood pressure.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT07031739

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.