Condition
Transfemoral Amputation clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Transfemoral Amputation clinical trials that are recruiting, at sites in 2 countries (most in United States (5), Turkey (Türkiye) (1)). By phase: Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 2Countries
Newest Transfemoral Amputation clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Personalizing powered knee prostheses using reinforcement learning | Phase 1 | Raleigh, North Carolina | Recruiting | Oct 2, 2025 |
| Neural-controlled powered knee and ankle for people with above-knee amputation. | — | Cambridge, Massachusetts | Recruiting | Oct 2, 2025 |
| How residual limb length relates to strength, balance, and function after transfemoral amputation | — | Ankara, Ankara | Recruiting | Jun 22, 2025 |
| Evaluating the Ossur Power Knee for people with above-knee amputations | — | Chicago, Illinois | Recruiting | Jan 23, 2024 |
| Improving prosthetic socket fit for veterans with lower limb amputations | — | Aurora, Colorado | Recruiting | Aug 14, 2023 |
| Comparing walking with powered and passive prosthetic knees for amputees | — | Loma Linda, California | Recruiting | Apr 26, 2023 |
All recruiting trials (6)
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Personalizing powered knee prostheses using reinforcement learning
This trial will test whether a computer system called RISE can help clinicians tune powered knee prostheses faster and make them work better for people with above-knee (transfemoral) amputations.
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Neural-controlled powered knee and ankle for people with above-knee amputation.
We will test whether a neural-controlled powered knee or ankle prosthesis helps people with above-knee (transfemoral) amputation walk more naturally and stably in everyday situations.
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How residual limb length relates to strength, balance, and function after transfemoral amputation
This study tests how the length of the missing lower leg segment affects strength, balance, and daily function in adults with a transfemoral amputation.
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Evaluating the Ossur Power Knee for people with above-knee amputations
This study is testing whether the Ossur Power Knee, a high-tech prosthetic knee that helps with movement, works better than a regular prosthetic knee for people with above-knee amputations.
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Improving prosthetic socket fit for veterans with lower limb amputations
This study is testing whether an adjustable prosthetic socket can help veterans with lower limb amputations walk better and feel more comfortable compared to a regular socket.
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Comparing walking with powered and passive prosthetic knees for amputees
This study tests whether walking with a powered prosthetic knee is easier and more efficient for people with leg amputations compared to using a standard knee.
Related topics
Quick answers
How many Transfemoral Amputation clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (5 trials), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.