Evaluating the Ossur Power Knee for people with above-knee amputations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This investigation aims to biomechanically evaluate the Ossur Power Knee, a microprocessor-controlled prosthetic knee that actively generates power during movement, and compare its performance to the Ossur Rheo XC, a conventional passive prosthetic knee. The study will assess how these devices affect walking and other activities in individuals with unilateral transfemoral amputation. Additionally, it will explore potential differences in mobility between male and female users. Participants will be monitored for their gait and overall mobility to determine the effectiveness of the powered knee joint.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Unilateral, transfemoral amputation (any etiology)
* Residual limb length classified as standard (i.e., medium) to long
* Prosthesis user for at least 1 year prior to enrolling in the study
* K3 or K4 level ambulator
* Good sensation on their residual limb(s) (upon routine clinical examination)
* Good skin integrity upon visual inspection
* Does not require the use of assistive devices to walk for short distances
* Not currently taking medications that are known to affect balance or gait
* Presents with good socket fit based upon a standard assessment by the study prosthetist

Exclusion Criteria:

* Bilateral amputations
* Individuals with a knee disarticulation

Where it's running

• Jesse Brown VA Medical Center, Chicago, IL
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Steven A Gard, PhD — Jesse Brown VA Medical Center, Chicago, IL
• Study coordinator: Rebecca Stine, MS
• Email: rebecca.stine@va.gov
• Phone: (312) 503-5726

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Personalizing powered knee prostheses using reinforcement learning

  This trial will test whether a computer system called RISE can help clinicians tune powered knee prostheses faster and make them work better for people with above-knee (transfemoral) amputations.

  Recruiting Phase 1 North Carolina State University · Raleigh, North Carolina · NCT07204925

• Neural-controlled powered knee and ankle for people with above-knee amputation.

  We will test whether a neural-controlled powered knee or ankle prosthesis helps people with above-knee (transfemoral) amputation walk more naturally and stably in everyday situations.

  Recruiting Massachusetts Institute of Technology · Cambridge, Massachusetts · NCT07204912

• How residual limb length relates to strength, balance, and function after transfemoral amputation

  This study tests how the length of the missing lower leg segment affects strength, balance, and daily function in adults with a transfemoral amputation.

  Recruiting Hacettepe University · Ankara, Ankara · NCT07032233

• Improving prosthetic socket fit for veterans with lower limb amputations

  This study is testing whether an adjustable prosthetic socket can help veterans with lower limb amputations walk better and feel more comfortable compared to a regular socket.

  Recruiting VA Office of Research and Development · Aurora, Colorado · NCT05989243

• Comparing walking with powered and passive prosthetic knees for amputees

  This study tests whether walking with a powered prosthetic knee is easier and more efficient for people with leg amputations compared to using a standard knee.

  Recruiting Loma Linda University · Loma Linda, California · NCT05831696

• Evaluating human movement with assistive devices

  This study tests how well different assistive devices help people with limb weakness or paralysis move around in everyday situations.

  Recruiting Orthocare Innovations, LLC · Edmonds, Washington · NCT05729061

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.