Condition

Syphilis Infection clinical trials and research

• 7Clinical trials
• 5Countries

Newest Syphilis Infection clinical trials

All recruiting trials (7)

• TruPlex HIV/HepB/Syphilis Rapid Test performance and usability in real-world settings

  This study tests how well the TruPlex rapid test detects HIV, hepatitis B, and syphilis using fingerstick and other blood samples, and whether trained operators find the test easy to use at point-of-care sites.

  Recruiting bioLytical Laboratories · Melbourne, Victoria · NCT07569913

• TruPlex rapid test for HIV, Hepatitis B, and syphilis performance and usability

  This project will test whether the TruPlex rapid test can accurately detect HIV, hepatitis B, and syphilis when used by trained healthcare workers on adults getting tested for these infections.

  Recruiting at 3 sites bioLytical Laboratories · Johannesburg, Gauteng and 2 other locations · NCT07563309

• Doxycycline after sex to prevent gonorrhea, chlamydia, and syphilis in MSM in Bangkok

  This research tests whether taking doxycycline after sex can prevent gonorrhea, chlamydia, and syphilis in men who have sex with men in Bangkok.

  Recruiting Phase 4 Bangrak STIs Center · Sathorn, Bangkok · NCT07397403

• Rapid syphilis testing at family planning visits in Hawai‘i

  This study checks if a quick fingerstick syphilis test done during a family planning visit is practical and acceptable for patients.

  Recruiting Queen's Medical Center · Honolulu, Hawaii · NCT07358949

• New ALPCO blood tests to detect syphilis antibodies

  This will test two ALPCO blood tests that look for treponemal and non-treponemal antibodies in people screened for or suspected of having syphilis, including pregnant and HIV-positive individuals.

  Recruiting at 6 sites American Laboratory Products Company · Lancaster, California and 5 other locations · NCT07089836

• Multiplo HIV and syphilis self-test for adults

  This project will see if adults seeking HIV or syphilis testing can correctly use the Multiplo HIV/syphilis self-test to get accurate results.

  Recruiting at 3 sites Unity Health Toronto · Victoria, British Columbia and 2 other locations · NCT06716450

• Using lidocaine to reduce pain from benzathine penicillin injections for syphilis treatment

  This study is testing if adding lidocaine to syphilis treatment injections can help reduce the pain patients feel during and after the shot.

  Recruiting Phase 3 Washington University School of Medicine · St Louis, Missouri · NCT06391125

Related topics

Quick answers

How many Syphilis Infection clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (3 trials), Thailand (1 trial), Canada (1 trial), Australia (1 trial), South Africa (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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