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Semaglutide clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Semaglutide clinical trials that are recruiting, at sites in 3 countries (most in United States (1), China (1), Canada (1)). By phase: Phase 3 (1), Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 3Countries
Newest Semaglutide clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Semaglutide's effects on heart and muscle mass | — | Edmonton, Alberta | Recruiting | Dec 9, 2025 |
| Semaglutide versus calorie restriction for adults with type 2 diabetes | Phase 4 | Jiangxi, Nanchang | Recruiting | Dec 9, 2025 |
| Early reinitiation of semaglutide after sleeve gastrectomy in youth | Phase 3 | Los Angeles, California | Recruiting | Apr 18, 2025 |
All recruiting trials (3)
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Semaglutide's effects on heart and muscle mass
This project will use MRI scans and strength tests over 12 months to see if semaglutide changes body and heart muscle in adults starting the medication.
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Semaglutide versus calorie restriction for adults with type 2 diabetes
This study will test whether 12 weeks of semaglutide injections or a reduced-calorie diet better improves blood sugar, weight, liver fat, and inflammation in adults newly diagnosed with type 2 diabetes.
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Early reinitiation of semaglutide after sleeve gastrectomy in youth
In youths aged 12–18 with severe obesity who had sleeve gastrectomy and were taking semaglutide, this study tests whether restarting semaglutide two weeks after surgery for 24 months leads to better weight and metabolic outcomes than standard care without drugs.
Related topics
Quick answers
How many Semaglutide clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (1 trial), China (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.