Condition
PSC clinical trials and research
As of November 12, 2026, Find a Trial lists 5 PSC clinical trials that are recruiting, at sites in 7 countries (most in United States (3), Italy (2), Switzerland (1)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 7Countries
Newest PSC clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Preventing recurrence of primary sclerosing cholangitis after liver transplantation | Phase 2 | Scottsdale, Arizona | Recruiting | Apr 1, 2025 |
| Colangioids to find genetic causes of atypical primary sclerosing cholangitis | — | Milan, MI | Recruiting | Mar 10, 2025 |
| Observational cohort of adults with primary sclerosing cholangitis | — | Sacramento, California and 17 other locations | Recruiting | Mar 7, 2024 |
| Collecting bile samples from patients with Primary Sclerosing Cholangitis and controls | — | Rochester, Minnesota | Recruiting | Feb 15, 2021 |
| Swiss Primary Sclerosing Cholangitis Cohort | — | Lugano, Canton Ticino and 20 other locations | Recruiting | May 10, 2017 |
All recruiting trials (5)
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Preventing recurrence of primary sclerosing cholangitis after liver transplantation
This study is testing if a daily medication called fenofibrate can help prevent primary sclerosing cholangitis from coming back in people who have had a liver transplant.
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Colangioids to find genetic causes of atypical primary sclerosing cholangitis
This project will use lab-grown bile duct organoids (colangioids) to test which genetic changes are linked to atypical primary sclerosing cholangitis in adults with confirmed or suspected PSC or in available liver tissue.
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Observational cohort of adults with primary sclerosing cholangitis
This study is collecting health information from adults with primary sclerosing cholangitis to help understand the condition better and improve future treatments.
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Collecting bile samples from patients with Primary Sclerosing Cholangitis and controls
This study is collecting bile samples from people with Primary Sclerosing Cholangitis and healthy individuals to see how the disease affects the body and find new ways to treat it.
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Swiss Primary Sclerosing Cholangitis Cohort
This project will collect blood and other biological samples plus health information from people with primary sclerosing cholangitis in Switzerland to try to better understand the disease course and treatment responses.
Related topics
Quick answers
How many PSC clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 7 countries. The most sites are in United States (3 trials), Italy (2 trials), Switzerland (1 trial), Canada (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.