Condition

Progressive Glioblastoma clinical trials and research

• 2Clinical trials
• 1Country

All recruiting trials (2)

• GI-102 With or Without Pembrolizumab Before Surgery for Recurrent or Progressive Grade 4 Gliomas

  The team will test whether giving GI-102 alone or together with pembrolizumab before surgery helps adults with recurrent or progressive IDH‑wildtype glioblastoma or IDH‑mutant grade 4 astrocytoma.

  Recruiting Phase 2 Mayo Clinic · Rochester, Minnesota · NCT07301268

• Sonodynamic therapy using SONALA-001 or 5-ALA with MRI-guided focused ultrasound for progressive or recurrent glioblastoma

  This trial tries giving SONALA-001 (IV) or 5-ALA (oral) together with MRI-guided focused ultrasound to see if the combination is safe and can help people whose glioblastoma has progressed or come back.

  Recruiting Early Phase 1 Mayo Clinic · Rochester, Minnesota · NCT07076472

Related topics

Quick answers

How many Progressive Glioblastoma clinical trials are recruiting right now?

2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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