Condition

Prognostic Stage IV Breast Cancer AJCC v8 clinical trials and research

• 9Clinical trials
• 3Countries

Newest Prognostic Stage IV Breast Cancer AJCC v8 clinical trials

All recruiting trials (9)

• Personalized tumor vaccine with checkpoint inhibitors for triple negative breast cancer

  This phase I trial will test whether a personalized tumor membrane vesicle (TMV) vaccine, given alone or with pembrolizumab or ipilimumab, can boost immune response and help control disease in adults with triple negative breast cancer.

  Recruiting at 4 sites Phase 1 Emory University · Atlanta, Georgia and 3 other locations · NCT06324240

• Using minoxidil to treat hair loss in breast cancer patients on endocrine therapy

  This study is testing if a hair loss treatment called minoxidil, given either as a foam or a pill, can help women with breast cancer who are losing their hair due to cancer therapy.

  Recruiting Early Phase 1 Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT05417308

• Combining Tumor Treating Fields with Cabozantinib or Pembrolizumab and Nab-Paclitaxel for Advanced Solid Tumors

  This study is testing a new treatment that combines tumor treating fields with two different cancer drugs to see if it helps people with advanced solid tumors in the abdomen or chest.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT05092373

• Avapritinib for treating advanced solid tumors with specific mutations

  This study is testing if a new drug called avapritinib can help people with advanced solid tumors that have specific mutations feel better and live longer after other treatments haven't worked.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04771520

• Investigating biomarkers and clinical features in metastatic breast cancer patients treated with CDK4/6 inhibitors

  This study is trying to learn more about how metastatic breast cancer patients respond to CDK4/6 inhibitors by looking at their medical records and collecting blood and tissue samples to understand the cancer better.

  Recruiting Roswell Park Cancer Institute · Buffalo, New York · NCT04526587

• Dendritic cell vaccines and pembrolizumab for treating brain metastasis from breast cancer

  This study is testing a new vaccine combined with an immune therapy to see if it can help people with brain metastasis from triple negative or HER2+ breast cancer fight their cancer better.

  Recruiting at 2 sites Phase 2 Roswell Park Cancer Institute · Tampa, Florida and 2 other locations · NCT04348747

• Using abemaciclib to treat older patients with hormone receptor positive breast cancer

  This study is testing if the medication abemaciclib can safely help older patients with hormone receptor positive breast cancer feel better and live longer.

  Recruiting at 6 sites Phase 2 City of Hope Medical Center · Duarte, California and 5 other locations · NCT04305834

• Combining Olaparib with Cediranib or AZD6738 for Advanced Breast Cancer with BRCA Mutations

  This study is testing if combining the drugs olaparib with either cediranib or AZD6738 can help women with advanced breast cancer that has BRCA mutations feel better after they’ve already tried other treatments.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04090567

• Monitoring breast cancer using serum tumor markers

  This study is testing if using blood tests to monitor hormone receptor positive, HER2 negative metastatic breast cancer can help patients live as long as those who receive standard monitoring while also looking at costs and how patients feel.

  Recruiting at 592 sites SWOG Cancer Research Network · Anchorage, Alaska and 722 other locations · NCT03723928

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Quick answers

How many Prognostic Stage IV Breast Cancer AJCC v8 clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (9 trials), Guam (1 trial), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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