Condition

Procedural Pain clinical trials and research

• 13Clinical trials
• 1New in 30 days
• 5Countries

Newest Procedural Pain clinical trials

All recruiting trials (13)

• Ketamine and optic nerve swelling during procedural pain relief

  This study tests whether giving ketamine for procedural pain relief changes the optic nerve sheath diameter in adults, using bedside ultrasound before and after dosing to see if intracranial pressure shifts differ by ketamine dose.

  Recruiting Ankara Etlik City Hospital · Ankara, Etlik · NCT07916064

• Using a stress ball during a breast biopsy

  We’re testing whether using a stress ball during a breast biopsy helps reduce pain and anxiety and stabilizes vital signs in patients.

  Recruiting TC Erciyes University · Kayseri · NCT07844395

• VR distraction, EMLA cream, or standard care for kids' blood draws

  A randomized trial tests whether virtual reality distraction helps reduce pain during blood draws in children aged 3 to 15 compared with EMLA cream or standard care.

  Recruiting Jan Evangelista Purkyne University · Ústí nad Labem, Ústí nad Labem Region · NCT07763132

• Kangaroo Care by Mother or Nurse to Reduce Pain During Phototherapy in Newborns

  This study tests whether mother-administered or nurse-administered kangaroo care during a heel-stick procedure reduces pain in newborns with hyperbilirubinemia, compared with standard care.

  Recruiting Marmara University · Istanbul · NCT07761689

• Distraction Cards vs Emotion-Regulation Toy Squeezing During Vaccination for Preschoolers

  This trial tests whether distraction cards or emotion-regulation toy squeezing better reduce pain and fear during an intramuscular tetanus shot for 4- to 7-year-olds.

  Recruiting Mersin University · Mersin, Province · NCT07669961

• Rhythmic Skin Tapping and Internal Vibration for Pediatric Venipuncture Pain and Fear

  This study tests whether light fingertip tapping above the needle site or a humming sound can reduce pain and fear in children aged 6-12 during blood draws.

  Recruiting Akdeniz University · Antalya, Kepez · NCT07650591

• Intranasal vs IV fentanyl for procedural pain in preterm newborns

  This trial will test whether a nasal spray or an intravenous dose of fentanyl works better to relieve short-term procedure pain in preterm newborns.

  Recruiting Early Phase 1 Ain Shams University · Cairo · NCT07190625

• Virtual reality to reduce pain during ultrasound-guided obstetric needle procedures

  This study will try virtual reality during ultrasound-guided needle procedures to see if it reduces pain and anxiety for obstetric patients.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07094451

• Using virtual reality to manage pain and anxiety during burn wound care

  This study tests if using virtual reality can help adults with burn injuries feel less pain and anxiety during their dressing changes compared to watching a nature video.

  Recruiting Al Hayah University In Cairo · Cairo · NCT06913270

• Preparing the cervix for same-day second‑trimester D&E

  This research tests whether a single‑balloon catheter works as well as osmotic dilators to prepare the cervix for same‑day D&E in people 16 weeks 0 days to 18 weeks 6 days pregnant.

  Recruiting Boston Medical Center · Boston, Massachusetts · NCT06799052

• Relaxing virtual reality glasses during non-emergency oral surgery

  This trial will test whether wearing relaxing virtual reality (VR) glasses during non-emergency oral surgery with IV sedation helps patients feel more comfortable and need less sedative medication.

  Recruiting Boston University · Boston, Massachusetts · NCT06723158

• Using self-adjusted nitrous oxide to manage pain and anxiety during vasectomy

  This study is testing if letting patients control their nitrous oxide levels during a vasectomy can help reduce their pain and anxiety.

  Recruiting Phase 4 Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT05895383

• Using virtual reality to ease pain during medical procedures for young cancer patients

  This study is testing if virtual reality can help young cancer patients feel less pain and anxiety during medical procedures compared to standard treatments.

  Recruiting Poitiers University Hospital · Poitiers · NCT05275881

Related topics

Quick answers

How many Procedural Pain clinical trials are recruiting right now?

13, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in Turkey (Türkiye) (5 trials), United States (4 trials), Egypt (2 trials), France (1 trial), Czechia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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