Condition
Primary Lateral Sclerosis clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Primary Lateral Sclerosis clinical trials that are recruiting, at sites in 2 countries (most in United States (3), Canada (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Primary Lateral Sclerosis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Research network for hereditary spastic paraplegia and primary lateral sclerosis | — | Miami, Florida and 10 other locations | Recruiting | Aug 14, 2024 |
| Platform to analyze and understand ALS | — | Edmonton, Alberta and 3 other locations | Recruiting | Jan 24, 2022 |
| Research to gather clinical data on ALS and related disorders | — | Irvine, California and 10 other locations | Recruiting | Apr 5, 2018 |
| MRI markers for ALS and PLS | — | Minneapolis, Minnesota | Recruiting | Oct 2, 2015 |
All recruiting trials (4)
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Research network for hereditary spastic paraplegia and primary lateral sclerosis
This study is trying to learn more about hereditary spastic paraplegia and primary lateral sclerosis by enrolling people with specific types of the condition to help find better treatments and understand how these diseases progress.
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Platform to analyze and understand ALS
This study is trying to gather and analyze a lot of information about ALS and related disorders by having participants, including healthy individuals, come in for check-ups and tests over a year to help improve future research.
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Research to gather clinical data on ALS and related disorders
This study is collecting health information from people with ALS and similar disorders to better understand these conditions and help improve future treatments.
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MRI markers for ALS and PLS
The study will use 3T and 7T MRI scans to see if specific brain imaging markers differ between people with ALS or PLS and healthy volunteers.
Related topics
Quick answers
How many Primary Lateral Sclerosis clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.