Condition

Portal Hypertension Related to Cirrhosis clinical trials and research

• 12Clinical trials
• 1New in 30 days
• 8Countries

Newest Portal Hypertension Related to Cirrhosis clinical trials

All recruiting trials (12)

• Endovascular treatment outcomes after portal hypertension–related GI bleeding in cirrhosis

  This study tests how well endovascular procedures for portal hypertension–related GI bleeding work in adults with cirrhosis, and what factors predict outcomes.

  Recruiting University Medical Center Ho Chi Minh City (UMC) · Ho Chi Minh City · NCT07918378

• Factors that affect reopening of blocked portal veins in people with cirrhosis and gastroesophageal varices

  This project looks at past records and follow-up to see which factors are linked with reopening (recanalization) of blocked portal veins in people who have cirrhosis and endoscopy-confirmed gastroesophageal varices.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07473375

• VIATORR TIPS 6–10 mm: Real-world use in cirrhosis with portal hypertension

  A real-world registry is seeing how the GORE VIATORR TIPS Endoprosthesis with Controlled Expansion 6-10 mm works over 2 years in adults with cirrhosis and portal hypertension.

  Recruiting at 5 sites W.L.Gore & Associates · Atlanta, Georgia and 4 other locations · NCT07390344

• MRI versus ultrasound for early liver cancer detection, body composition, and decompensation risk in cirrhosis

  This project will test whether abbreviated MRI or ultrasound is better at finding early liver cancer and measuring muscle and fat in adults with cirrhosis.

  Recruiting Linkoeping University · Linköping, Select A State Or Province · NCT07291141

• TIPS procedure with or without oral branched-chain amino acids (BCAA)

  This test will try giving oral BCAA supplements for three months after TIPS in adults with cirrhosis and sarcopenia to see if it improves muscle and clinical outcomes.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07281846

• Microplastics in the liver of people with cirrhosis and portal hypertension

  This study tests whether microplastics and nanoparticles accumulate in the livers of adults with cirrhosis and portal hypertension who are undergoing surgery or transplant, to understand where they go and what form they take.

  Recruiting at 2 sites Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh, Chandigarh and 1 other locations · NCT07280390

• 2D-shear wave spleen elastography to detect clinically significant portal hypertension and high-risk esophageal varices

  This study tests whether a 2D-shear wave spleen ultrasound can rule in or rule out clinically significant portal hypertension and high‑risk esophageal varices in adults with advanced chronic liver disease.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, Italia · NCT07122622

• Using TIPS before sleeve gastrectomy to improve outcomes for people with cirrhosis and severe obesity

  This trial tests whether placing a TIPS (a portal decompression procedure) before sleeve gastrectomy helps adults with cirrhosis, clinically significant portal hypertension, and severe obesity lose weight, feel better, and have fewer complications.

  Recruiting Phase 4 The Cleveland Clinic · Cleveland, Ohio · NCT07058155

• Carvedilol effect on portal pressure measured by endoscopic ultrasound

  We will test whether one month of carvedilol (titrated to 12.5 mg daily) lowers portal pressure to help prevent digestive bleeding in adults with cirrhosis.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand and 1 other locations · NCT06861075

• Effects of Metformin on Portal Hypertension in Cirrhosis Patients

  This study is testing if metformin can lower blood pressure in the liver for people with cirrhosis and portal hypertension who haven't had enough success with other treatments.

  Recruiting Phase 2 Assistance Publique - Hôpitaux de Paris · Clichy, France · NCT06687265

• Using TIPS Stent Graft to treat complications of cirrhosis and portal hypertension

  This study is testing if a special stent can help people with liver cirrhosis and high blood pressure in the liver feel better and avoid serious complications over a year.

  Recruiting C. R. Bard · Changsha, Hunan · NCT06669806

• Assessing portal pressure response to beta-blockers using endoscopic ultrasound

  This study is testing if using endoscopic ultrasound to measure portal pressure can help doctors see how well beta-blockers work for people with cirrhosis and high blood pressure in the liver.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06513195

Related topics

Quick answers

How many Portal Hypertension Related to Cirrhosis clinical trials are recruiting right now?

12, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in China (3 trials), United States (2 trials), Italy (2 trials), France (2 trials), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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