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PD-1 clinical trials and research

• 8Clinical trials
• 2Countries

Newest PD-1 clinical trials

All recruiting trials (8)

• PD-1–edited tumor-infiltrating T cells for advanced colorectal cancer

  This test uses a patient's own tumor-infiltrating T cells, edited to remove PD‑1, to see if the treatment is safe and may help adults with advanced colorectal cancer who no longer have standard treatment options.

  Recruiting Phase 1 Ruijin Hospital · Shanghai, None Selected · NCT07035002

• Testing a blood test to predict response to cancer immunotherapy

  This study is testing a blood test to see if it can predict how well people with advanced cancer will respond to a specific type of immunotherapy.

  Recruiting at 3 sites Oxford Biodynamics Inc. · Norwich, Connecticut and 2 other locations · NCT06635954

• Combining Tirellizumab with chemotherapy for early oral cancer treatment

  This study is testing if combining a new drug called Tirellizumab with chemotherapy can help people with early-stage oral cancer avoid surgery and improve their treatment outcomes.

  Recruiting Phase 2 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06130332

• Comparing PD-1 inhibitor therapy to radiotherapy for advanced head and neck cancer after immunochemotherapy

  This study is testing if a new type of cancer treatment called PD-1 inhibitor therapy can be a better option than regular radiotherapy for patients with advanced head and neck cancer who have responded well to earlier treatment.

  Recruiting Phase 3 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT05980715

• Comparing two and four courses of pembrolizumab with chemotherapy for head and neck cancer

  This study is testing whether getting two or four rounds of a new cancer drug along with chemotherapy helps people with head and neck cancer do better before surgery.

  Recruiting Phase 2 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT05980702

• Monitoring the safety of Sintilimab in Chinese patients

  This study is testing how safe Sintilimab is for Chinese patients by closely watching for any side effects while they receive the treatment.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality · NCT04840355

• Combining Toripalimab with Surgery for Recurrent Nasopharyngeal Carcinoma

  This study is testing whether adding a new drug called Toripalimab to surgery can help people with recurrent nasopharyngeal cancer live longer and have better outcomes than surgery alone.

  Recruiting Phase 3 Sun Yat-sen University · Guangzhou, Guangdong and 6 other locations · NCT04778956

• Examining the link between vitamin D levels and thyroid toxicity in cancer immunotherapy

  This study is trying to see if having low vitamin D levels affects the chances of developing thyroid problems in cancer patients receiving immunotherapy.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT04615988

Related topics

Quick answers

How many PD-1 clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (6 trials), United States (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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