Condition

MSI-H Cancer clinical trials and research

• 4Clinical trials
• 10Countries

Newest MSI-H Cancer clinical trials

All recruiting trials (4)

• IParomlimab and Tuvonralimab with first-line therapy for MSI-H gastric cancer

  This phase 2 trial tests whether adding iparomlimab or tuvonralimab to standard first-line chemotherapy and PD-1/PD-L1 therapy helps people with MSI-H, recurrent or metastatic gastric cancer.

  Recruiting at 10 sites Phase 2 Peking University · Shijiazhuang, Hebei and 9 other locations · NCT07127822

• Oral MOMA-341 for advanced or metastatic MSI-H or dMMR solid tumors

  This trial will test whether the oral drug MOMA-341, alone or with irinotecan or immunotherapy, can be safe and show anti-tumor activity in adults with advanced or metastatic MSI-H/dMMR solid tumors who have progressed after prior PD-(L)1 therapy.

  Recruiting at 13 sites Phase 1 MOMA Therapeutics · Phoenix, Arizona and 14 other locations · NCT06974110

• Assessing a new treatment for advanced solid tumors

  This study is testing a new medication for people with advanced solid tumors to see if it is safe, how well it works, and what side effects it may cause.

  Recruiting at 21 sites Phase 1/2 Nimbus Therapeutics · Los Angeles, California and 21 other locations · NCT06898450

• Combination therapy with atezolizumab and tiragolumab for solid tumors

  This study is testing a new combination treatment using two immune-boosting drugs for people with solid tumors, like melanoma and head and neck cancers, to see if it can help them fight their cancer better than current treatments.

  Recruiting Phase 2 University Medical Center Groningen · Groningen · NCT05483400

Related topics

Quick answers

How many MSI-H Cancer clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in Australia (2 trials), United States (2 trials), China (1 trial), Netherlands (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →