Condition

Mismatch Repair Deficiency clinical trials and research

• 6Clinical trials
• 4Countries

Newest Mismatch Repair Deficiency clinical trials

All recruiting trials (6)

• Liquid biopsy and machine learning to detect early colorectal cancer, advanced adenomas, Lynch-related cancers, and residual disease

  This project will test a blood-based liquid biopsy that uses microRNA signals and machine learning to detect colorectal cancer, advanced adenomas, Lynch-associated cancers, and molecular residual disease in people who have a colonoscopy.

  Recruiting San Raffaele University · Milan, Lombardy and 3 other locations · NCT07450612

• Combination of Toripalimab and Celecoxib for Advanced Colorectal Cancer

  This study is testing if a combination of two medications, Toripalimab and Celecoxib, can help patients with advanced colorectal cancer avoid surgery and improve their treatment outcomes.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT06903858

• PD-1 inhibitor with progesterone to preserve fertility in early‑stage MMRd endometrial cancer

  This study tests whether giving a PD-1 inhibitor together with progesterone can help young patients with early, MMRd endometrial cancer preserve fertility.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT06549855

• Oral Alintegimod with Ipilimumab followed by Nivolumab for advanced cancer

  This study is testing if a new oral medication called Alintegimod, combined with two other cancer treatments, can help people with advanced solid tumors feel better and live longer.

  Recruiting at 4 sites Phase 1/2 7 Hills Pharma, LLC · Aurora, Colorado and 4 other locations · NCT06362369

• Combining chemotherapy with Toripalimab for advanced gastric cancer

  This study is testing if combining a specific chemotherapy with Toripalimab can help people with advanced gastric cancer feel better and improve their treatment results.

  Recruiting Phase 2 First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang and 7 other locations · NCT05729646

• AI-based precision oncology clinical trial matching and registry

  This study is testing whether an AI tool can help match cancer patients with the right clinical trials based on their specific cancer details to see if it improves their chances of getting into trials and their overall outcomes.

  Recruiting at 68 sites Massive Bio, Inc. · Birmingham, Alabama and 67 other locations · NCT03452774

Related topics

Quick answers

How many Mismatch Repair Deficiency clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in China (3 trials), United States (2 trials), Italy (1 trial), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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