Condition
Medication Overuse Headache clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Medication Overuse Headache clinical trials that are recruiting, at sites in 4 countries (most in China (2), Turkey (Türkiye) (1), Thailand (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 4Countries
Newest Medication Overuse Headache clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Greater Occipital Nerve Block for Migraine with Medication Overuse Headache | — | Bangkok, Bangkok and 2 other locations | Recruiting | May 5, 2026 |
| Personalized pulsed radiofrequency treatment of the greater occipital nerve for medication overuse headache | — | Ankara | Recruiting | Jan 22, 2026 |
| i-NEED: New migraine drugs database | — | Milan, Italy and 1 other locations | Recruiting | Aug 5, 2025 |
| Electroacupuncture to reduce medication-overuse headache and explore effects on the central nervous system | — | Beijing, Beijing Municipality | Recruiting | Jan 31, 2025 |
| China Headache Disorders Registry (CHAIRS) for People with Migraine and Other Primary Headaches | — | Anqing, Anhui and 60 other locations | Recruiting | Apr 19, 2022 |
All recruiting trials (5)
-
Greater Occipital Nerve Block for Migraine with Medication Overuse Headache
This study will test whether a nerve block using lidocaine and methylprednisolone can help people with migraine who overuse medications to reduce withdrawal headaches during detoxification.
-
Personalized pulsed radiofrequency treatment of the greater occipital nerve for medication overuse headache
This trial will try pulsed radiofrequency applied to the greater occipital nerve, given either early or after an initial month of standard care, to see if it reduces monthly headache days in adults with medication overuse headache.
-
i-NEED: New migraine drugs database
This project will collect real-life data to see how new migraine treatments—anti‑CGRP antibodies, gepants, ditans, and a sumatriptan‑naproxen combo—work and how well adults with episodic or chronic migraine tolerate them.
-
Electroacupuncture to reduce medication-overuse headache and explore effects on the central nervous system
This trial will test whether electroacupuncture can lower the number of headache days and reduce medication use in people with medication-overuse headache.
-
China Headache Disorders Registry (CHAIRS) for People with Migraine and Other Primary Headaches
This project will collect clinical, imaging, biomarker, genetic, and treatment outcome data from people aged 12 and older with primary headache disorders, including migraine and medication‑overuse headache, to see if patterns predict outcomes and guide care.
Related topics
Quick answers
How many Medication Overuse Headache clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in China (2 trials), Turkey (Türkiye) (1 trial), Thailand (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.