Condition
Mania clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Mania clinical trials that are recruiting, at sites in 15 countries (most in United States (2), Argentina (1), Bulgaria (1)). By phase: Phase 2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 15Countries
Newest Mania clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| NBI-1117568 for adults with Bipolar I disorder experiencing current mania | Phase 2 | Little Rock, Arkansas and 10 other locations | Recruiting | Dec 17, 2025 |
| KarXT added to lithium, valproate, or lamotrigine for treating mania in Bipolar I | Phase 3 | Bentonville, Arkansas and 108 other locations | Recruiting | Aug 26, 2025 |
| Improving mental health care in West Africa using mobile health and nurse support | — | Accra | Recruiting | Jan 30, 2023 |
| Investigating Mania Induced by Deep Brain Stimulation in Parkinson's Disease | — | Lisbon | Recruiting | Jul 6, 2022 |
All recruiting trials (4)
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NBI-1117568 for adults with Bipolar I disorder experiencing current mania
This trial will test whether NBI-1117568 reduces manic symptoms in adults with Bipolar I disorder who are currently having a manic episode.
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KarXT added to lithium, valproate, or lamotrigine for treating mania in Bipolar I
This will test whether adding KarXT to a stable mood stabilizer (lithium, valproate, or lamotrigine) helps adults hospitalized for an acute manic episode of bipolar I disorder reduce their manic symptoms.
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Improving mental health care in West Africa using mobile health and nurse support
This study is testing whether a new approach that combines nurse support and a mobile health app can improve mental health care for people with serious mental illnesses in Ghanaian prayer camps.
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Investigating Mania Induced by Deep Brain Stimulation in Parkinson's Disease
This study looks at people with Parkinson's Disease who have had deep brain stimulation surgery to see if certain factors can help explain why some of them experience mania afterwards.
Related topics
Quick answers
How many Mania clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 15 countries. The most sites are in United States (2 trials), Argentina (1 trial), Bulgaria (1 trial), China (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.