Condition
Locally Advanced Oral Cavity Squamous Cell Carcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Locally Advanced Oral Cavity Squamous Cell Carcinoma clinical trials that are recruiting, at sites in 2 countries (most in United States (3), Canada (1)). By phase: Phase 2 (1), Phase 3 (1), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Locally Advanced Oral Cavity Squamous Cell Carcinoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Proton or Photon Radiotherapy Added to Pembrolizumab Before Surgery for Advanced or Recurrent Oral Cavity Cancer | Phase 2 | Rochester, Minnesota | Recruiting | Aug 25, 2026 |
| Radiation plus cetuximab vs radiation plus chemotherapy for advanced head and neck cancer patients who cannot receive cisplatin | Phase 3 | Birmingham, Alabama and 149 other locations | Recruiting | Mar 2, 2026 |
| Combining Ipatasertib with Chemotherapy and Radiation for Head and Neck Cancer | Phase 1 | Tampa, Florida and 17 other locations | Recruiting | Dec 29, 2021 |
All recruiting trials (3)
-
Proton or Photon Radiotherapy Added to Pembrolizumab Before Surgery for Advanced or Recurrent Oral Cavity Cancer
This phase 2 trial tests whether adding proton SFRT or SBRT to pembrolizumab before surgery helps patients with advanced or recurrent oral cavity cancer.
-
Radiation plus cetuximab vs radiation plus chemotherapy for advanced head and neck cancer patients who cannot receive cisplatin
This trial tests whether adding cetuximab to radiation works as well as, or better than, radiation with carboplatin and paclitaxel for people with advanced head and neck cancers who can’t have cisplatin.
-
Combining Ipatasertib with Chemotherapy and Radiation for Head and Neck Cancer
This study is testing if adding a new drug called ipatasertib to chemotherapy and radiation can help people with advanced head and neck cancer feel better and improve their treatment results.
Related topics
Quick answers
How many Locally Advanced Oral Cavity Squamous Cell Carcinoma clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (3 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.