Condition

Locally Advanced or Metastatic Solid Tumors clinical trials and research

• 17Clinical trials
• 8Countries

Newest Locally Advanced or Metastatic Solid Tumors clinical trials

All recruiting trials (17)

• ASP388B given alone or with standard therapies in solid tumors

  This early study tests ASP388B, first given alone or with standard cancer treatments, to see if it is safe and to find workable dose levels for solid tumors.

  Recruiting at 4 sites Phase 1/2 Astellas Pharma Inc · Lake Success, New York and 3 other locations · NCT07730021

• First-in-human test of EMB-15 in adults with advanced or metastatic solid tumors

  This early phase trial tests EMB-15 to see if it is safe and tolerable in adults whose solid tumors have progressed after standard care or have no standard therapy.

  Recruiting Phase 1 Shanghai EpimAb Biotherapeutics Co., Ltd. · Guangzhou, Guangdong · NCT07607054

• BC3195 plus pembrolizumab in advanced solid tumors

  This trial tests whether adding BC3195 to pembrolizumab is safe and shows preliminary activity in adults with locally advanced or metastatic solid tumors.

  Recruiting Phase 1/2 Biocity Biopharmaceutics Co., Ltd. · Guangzhou, Guangdong · NCT07469774

• YL202 for advanced non‑small cell lung, colorectal, cervical, and other solid tumors

  This trial will try YL202, an antibody‑drug conjugate that targets HER3, in adults with advanced non‑small cell lung, colorectal, cervical, or other metastatic solid tumors who have received one or two prior systemic treatments.

  Recruiting Phase 2 MediLink Therapeutics (Suzhou) Co., Ltd. · Changsha, Hunan · NCT07202364

• MRG007 (ARR-217) treatment for advanced solid tumors

  This trial will test MRG007 (ARR-217), an antibody-drug conjugate that targets CDH17, in adults with unresectable locally advanced or metastatic solid tumors who have exhausted standard therapies.

  Recruiting at 21 sites Phase 1 ArriVent BioPharma, Inc. · Los Angeles, California and 20 other locations · NCT07066657

• Evaluating XB010 for patients with solid tumors

  This study is testing a new drug called XB010, alone and with another medication, to see if it can help people with advanced solid tumors who have few other treatment options.

  Recruiting at 18 sites Phase 1 Exelixis · Irvine, California and 19 other locations · NCT06545331

• Evaluating IBI3005 for advanced solid tumors

  This study is testing a new drug called IBI3005 to see if it is safe and how much of it can be given to people with advanced solid tumors that haven't responded to previous treatments.

  Recruiting Phase 1 Innovent Biologics (Suzhou) Co. Ltd. · Jinan, Shandong · NCT06418061

• Evaluating BL-M05D1 for advanced solid tumors

  This study is testing a new treatment called BL-M05D1 to see if it is safe and effective for people with advanced solid tumors who have run out of other treatment options.

  Recruiting Phase 1 Biokin (Shanghai) Biopharmaceutical Co., Ltd. · Beijing, Beijing Municipality · NCT06349811

• Investigating ANS014004 for advanced solid tumors

  This study is testing a new drug called ANS014004 to see if it is safe and effective for adults with advanced solid tumors.

  Recruiting at 10 sites Phase 1 Avistone Biotechnology Co., Ltd. · San Diego, California and 14 other locations · NCT06307795

• Investigating DA-4505 and Pembrolizumab for Advanced Solid Tumors

  This study is testing a new treatment called DA-4505, both alone and with Pembrolizumab, to see if it helps adults with advanced solid tumors.

  Recruiting at 2 sites Phase 1/2 Dong-A ST Co., Ltd. · Seoul and 1 other locations · NCT06293651

• Evaluating TYK-00540 for patients with advanced solid tumors

  This study is testing a new drug called TYK-00540 to see if it is safe and how well it works for adults with advanced solid tumors.

  Recruiting Phase 1 TYK Medicines, Inc · Hefei · NCT06246071

• Testing PTT-936 for advanced solid tumors

  This study is testing a new treatment called PTT-936 to see if it can safely help people with advanced solid tumors, both on its own and when combined with other therapies.

  Recruiting at 6 sites Phase 1/2 Pyrotech Therapeutics, Inc. · Beverly Hills, California and 5 other locations · NCT06244992

• Evaluating YL202 for Patients with Advanced Solid Tumors

  This study is testing a new treatment called YL202 to see if it can help people with advanced solid tumors like lung, breast, and head and neck cancers feel better.

  Recruiting at 48 sites Phase 2 MediLink Therapeutics (Suzhou) Co., Ltd. · Hefei, Anhui and 81 other locations · NCT06107686

• Using engineered stem cells to treat advanced solid tumors

  This study is testing a new type of stem cell treatment to see if it can help people with advanced solid tumors who haven't responded to other therapies.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing · NCT05699811

• Investigating AP203 for advanced solid tumors

  This study is testing a new treatment called AP203 to see if it can help adults with advanced solid tumors, like lung cancer and head and neck cancer, feel better and fight their disease.

  Recruiting Phase 1/2 AP Biosciences Inc. · Taipei · NCT05473156

• Assessing ATG-037 and Pembrolizumab for Advanced Solid Tumors

  This study is testing a new treatment called ATG-037, both alone and with Pembrolizumab, to see if it can help people with advanced solid tumors.

  Recruiting at 5 sites Phase 1 Antengene Corporation · Sydney, New South Wales and 7 other locations · NCT05205109

• XZP-5955 tablets for patients with specific advanced solid tumors

  This study is testing if XZP-5955 tablets can help patients with advanced solid tumors that have specific gene changes, especially those who have run out of other treatment options.

  Recruiting Phase 1/2 Xuanzhu Biopharmaceutical Co., Ltd. · Beijing, Beijing Municipality · NCT04996121

Related topics

Quick answers

How many Locally Advanced or Metastatic Solid Tumors clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in China (13 trials), United States (5 trials), Australia (1 trial), Canada (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 8, Phase 1/2: 7, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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