Condition
Large Cell Neuroendocrine Carcinoma of the Lung clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Large Cell Neuroendocrine Carcinoma of the Lung clinical trials that are recruiting, at sites in 6 countries (most in United States (2), Canada (1), Japan (1)). By phase: Phase 1 (1), Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 6Countries
Newest Large Cell Neuroendocrine Carcinoma of the Lung clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Phase I testing of 225Ac-ETN029 for advanced DLL3-positive tumors | Phase 1 | Iowa City, Iowa and 7 other locations | Recruiting | Jun 5, 2025 |
| Radiation plus tarlatamab for DLL3-expressing tumors | Phase 1/2 | Gilbert, Arizona and 2 other locations | Recruiting | Feb 7, 2025 |
| Combining Durvalumab with Etoposide and Platinum for Lung Cancer Treatment | Phase 2 | Aix-en-Provence and 30 other locations | Recruiting | May 1, 2024 |
All recruiting trials (3)
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Phase I testing of 225Ac-ETN029 for advanced DLL3-positive tumors
This trial will test 225Ac-ETN029, with 111In-ETN029 used for imaging, to see if the treatment is safe, tolerable, and shows early anti-tumor activity in adults with advanced DLL3-positive neuroendocrine cancers.
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Radiation plus tarlatamab for DLL3-expressing tumors
This trial will test whether giving tarlatamab together with standard palliative or consolidative radiation is safe for adults with DLL3-expressing or DLL3-prevalent tumors such as melanoma, medullary thyroid cancer, sinonasal undifferentiated carcinoma, esthesioneuroblastoma, and bladder cancer.
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Combining Durvalumab with Etoposide and Platinum for Lung Cancer Treatment
This study is testing if combining a new immune therapy with chemotherapy can help people with advanced lung cancer feel better and live longer.
Related topics
Quick answers
How many Large Cell Neuroendocrine Carcinoma of the Lung clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 6 countries. The most sites are in United States (2 trials), Canada (1 trial), Japan (1 trial), South Korea (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.