Drug or treatment

Prednisone clinical trials

• 35Clinical trials
• 1New in 30 days
• 12Countries

Newest trials

All recruiting trials (35)

• Polatuzumab Vedotin plus Rituximab with Reduced-dose chemo for frail seniors with DLBCL

  This trial tests whether a gentler, first-line treatment (Polatuzumab Vedotin with Rituximab and reduced-dose chemo) helps older, frail patients with DLBCL stay disease-free longer.

  Recruiting Phase 4 The First Hospital of Jilin University · Changchun, Jilin · NCT07908888

• Orelabrutinib plus Pola-R-CHP as first-line treatment for intermediate- to high-risk DLBCL

  This trial tests whether adding orelabrutinib to the Pola-R-CHP regimen can improve outcomes for adults with intermediate- to high-risk newly diagnosed DLBCL.

  Recruiting at 2 sites The First Affiliated Hospital of Xiamen University · Xiamen, Fujian and 1 other locations · NCT07778212

• Mycophenolate mofetil with prednisone for immune-related hepatitis from cancer therapy

  This study tests whether starting mycophenolate mofetil plus prednisone can help liver inflammation caused by immune checkpoint inhibitors in adults with moderate to severe immune-related hepatitis.

  Recruiting Phase 2 Fox Chase Cancer Center · Philadelphia, Pennsylvania · NCT07663422

• PSMA-targeted therapy with hormone suppression for low-volume metastatic prostate cancer

  This phase II trial tests leuprolide acetate alone versus with 177Lu-PSMA-617 (with or without abiraterone acetate and prednisone) in men with hormone-sensitive, low-volume metastatic prostate cancer.

  Recruiting Phase 2 Mayo Clinic · Rochester, Minnesota · NCT07650240

• Post-op prednisone vs standard steroid regimen after knee or hip replacement

  This study tests a 5-day oral prednisone course after knee or hip replacement to see if pain, swelling, and glucose control are better or different than the usual intraoperative steroid approach.

  Recruiting Phase 4 Columbia University · New York, New York · NCT07630896

• Polatuzumab vedotin with Zanubrutinib, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone in untreated DLBCL (MCD/BN2/N1)

  This study tests a targeted combination therapy to see if it can treat previously untreated DLBCL with specific molecular subtypes.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT07608978

• BNT324 versus docetaxel for metastatic castration-resistant prostate cancer

  This trial will test whether BNT324, an antibody‑drug conjugate immunotherapy, works better than standard chemotherapy (docetaxel plus prednisone or prednisolone) for men with metastatic castration‑resistant prostate cancer who have had prior androgen‑receptor pathway inhibitors but no prior taxane chemotherapy for mCR

  Recruiting at 52 sites Phase 3 BioNTech SE · Santa Barbara, California and 51 other locations · NCT07365995

• Abiraterone and prednisone plus ADT versus ADT for PSMA-positive, conventionally node-negative prostate cancer

  This trial will test whether adding abiraterone and prednisone to standard androgen-deprivation therapy with radiation helps men whose prostate cancer shows PSMA uptake in small pelvic lymph nodes that are under 1 cm on conventional scans.

  Recruiting Phase 2 University of Nebraska · Omaha, Nebraska · NCT07237269

• Linperlisib plus CPT (cyclophosphamide, prednisone, thalidomide) for relapsed or refractory non-Hodgkin lymphoma

  This trial tests whether adding linperlisib to a CPT regimen helps adults with relapsed or refractory non-Hodgkin lymphoma.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT07195799

• Tislelizumab with cyclophosphamide, mitoxantrone liposomes, chidamide, and prednisone for newly diagnosed AITL

  This treatment tests whether adding the immunotherapy tislelizumab to chemotherapy (cyclophosphamide and mitoxantrone liposomes), the epigenetic drug chidamide, and prednisone helps adults newly diagnosed with angioimmunoblastic T‑cell lymphoma.

  Recruiting Phase 2 The Affiliated Hospital of Xuzhou Medical University · Xuzhou, Jiangsu · NCT07168317

• Epcoritamab plus dose‑adjusted EPOCH‑R for aggressive B‑cell lymphoma

  This trial tests whether adding epcoritamab to dose‑adjusted EPOCH‑R chemotherapy can safely improve outcomes for adults with untreated aggressive B‑cell non‑Hodgkin lymphoma.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT07097363

• Tislelizumab with cyclophosphamide, mitoxantrone liposomes, chidamide, and prednisone for relapsed or refractory angioimmunoblastic T-cell lymphoma

  This trial will test whether adding the immunotherapy tislelizumab to chemotherapy (cyclophosphamide and mitoxantrone liposomes) plus the epigenetic drug chidamide and prednisone helps adults with relapsed or refractory angioimmunoblastic T‑cell lymphoma.

  Recruiting Phase 2 The Affiliated Hospital of Xuzhou Medical University · Xuzhou, Jiangsu · NCT07058103

• Prednisone in adults with an immune-related subtype of autism

  This study tests whether prednisone, an anti-inflammatory drug, can help adults with a specific immune-related form of autism compared to a placebo.

  Recruiting Early Phase 1 Massachusetts General Hospital · Lexington, Massachusetts · NCT06934915

• Treatment for metastatic prostate cancer using HRS-1167 with other medications

  This study is testing if a new drug called HRS-1167, when taken with other medications, can safely help men with metastatic prostate cancer.

  Recruiting at 2 sites Phase 1/2 Jiangsu HengRui Medicine Co., Ltd. · Hefei, Anhui and 1 other locations · NCT06689163

• Combination therapy for elderly patients with newly diagnosed diffuse large B-cell lymphoma

  This study is testing a new combination treatment for older patients with newly diagnosed diffuse large B-cell lymphoma who can't tolerate standard chemotherapy to see if it helps them feel better and live longer.

  Recruiting Phase 1/2 Zhengzhou University · Zhengzhou, Henan · NCT06683885

• Comparing Ruxolitinib and Prednisone for treating chronic GVHD

  This study is testing whether Ruxolitinib works better than Prednisone for adults with chronic graft-versus-host disease who need treatment.

  Recruiting at 6 sites Phase 2 H. Lee Moffitt Cancer Center and Research Institute · Miami, Florida and 5 other locations · NCT06660355

• ViPOR combination therapy for relapsed or refractory aggressive B‑cell lymphoma

  This treatment will try a five‑drug targeted combination called ViPOR (venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) in adults whose aggressive B‑cell lymphoma has relapsed or not responded to prior therapy, focusing on specific genetic subtypes like CD10‑negative DLBCL and high‑grade B‑cell lympho

  Recruiting at 99 sites Phase 2 National Cancer Institute (NCI) · Tucson, Arizona and 114 other locations · NCT06649812

• Evaluating R-CMOP treatment for newly diagnosed diffuse large B-cell lymphoma

  This study is testing a new combination treatment for people with newly diagnosed diffuse large B-cell lymphoma to see if it is safe and effective.

  Recruiting Phase 1/2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT06594640

• Treatment of immune thrombocytopenia with hydroxychloroquine and prednisone

  This study is testing if a combination of hydroxychloroquine and prednisone can help adults with immune thrombocytopenia feel better and have longer-lasting results than just using prednisone alone.

  Recruiting at 7 sites Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality and 6 other locations · NCT06479304

• Using prednisone to treat pain after wrist fractures

  This study is testing if prednisone can help adults with wrist fractures feel less pain and recover better from Complex Regional Pain Syndrome.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT06453447

• Treatment for Richter Syndrome using Glofitamab with Rituximab or Obinutuzumab plus CHOP

  This study is testing if a new treatment combining Glofitamab with Rituximab or Obinutuzumab and CHOP chemotherapy can help people with untreated Richter Syndrome feel better.

  Recruiting at 6 sites Phase 2 French Innovative Leukemia Organisation · Amiens and 22 other locations · NCT06186648

• Comparing Abiraterone with Prednisone or Darolutamide for Advanced Prostate Cancer

  This study is testing whether a combination of abiraterone and prednisone works better than darolutamide alone for people with advanced prostate cancer by looking at side effects and changes in PSA levels over a year.

  Recruiting Phase 2 University of California, Davis · Sacramento, California · NCT06173362

• Comparing anti-inflammatory therapies for recurrent in-stent restenosis

  This study is testing whether adding low-dose colchicine or prednisone to standard drug therapy can help people with recurrent in-stent restenosis feel better and avoid heart problems after coronary treatment.

  Recruiting at 3 sites Phase 4 Fu Wai Hospital, Beijing, China · Beijing, Beijing Municipality and 3 other locations · NCT06090890

• Using oral prednisone to treat bone Langerhans cell histiocytosis in children and adolescents

  This study is testing if giving oral prednisone can help children and teenagers with bone Langerhans cell histiocytosis feel better compared to just watching their condition.

  Recruiting Phase 2 Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT06078969

• New combination therapy for untreated nodal TFH cell lymphoma

  This study is testing a new combination treatment for people with untreated angioimmunoblastic T-cell lymphoma to see if it helps them respond better to therapy.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT05958719

• Using Prednisone to Protect the Liver During Radiation Therapy for Liver Cancer

  This study is testing if taking Prednisone before and during radiation therapy can help protect the liver in patients with liver cancer.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05901519

• Combining immunotherapy with prednisone and sirolimus for kidney transplant recipients with advanced skin cancer

  This study is testing a new treatment that combines two immunotherapy drugs with prednisone and sirolimus to see if it helps kidney transplant recipients with advanced skin cancer while keeping their transplanted kidney safe.

  Recruiting at 25 sites Phase 1/2 National Cancer Institute (NCI) · La Jolla, California and 25 other locations · NCT05896839

• Treatment for Primary Mediastinal Large B-cell Lymphoma with Antibody Therapy and ImmunoChemotherapy

  This study is testing a new combination of antibody therapy and chemotherapy to see if it helps people with untreated primary mediastinal large B-cell lymphoma feel better and improve their quality of life.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04745949

• Treatment with Prednisone and Vitamin D for Elderly Patients with Lymphoma

  This study is testing if adding Vitamin D to the usual treatment with prednisone helps older patients with lymphoma do better during their cancer treatment.

  Recruiting at 21 sites Phase 3 Fondazione Italiana Linfomi - ETS · Brescia, BS and 48 other locations · NCT04442412

• High-dose steroid therapy for late lower cranial neuropathy in oropharyngeal cancer survivors

  This study tests whether high-dose prednisone or methylprednisolone can improve symptoms of late radiation-related lower cranial nerve problems in adults who survived oropharyngeal cancer.

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT04151082

• Evaluating how race and ethnicity affect treatment response in prostate cancer

  This study is testing how well standard prostate cancer treatments work for men of different races and ethnicities, especially African American men, to see if these factors affect their treatment outcomes.

  Recruiting at 2 sites Phase 2 Baylor College of Medicine · Houston, Texas and 2 other locations · NCT03833921

• Combination treatment for BCR-ABL positive B-cell leukemia and chronic myeloid leukemia

  This study is testing a new combination treatment for people with BCR-ABL positive B-cell leukemia or chronic myeloid leukemia to see if it helps them feel better and works well with existing medications.

  Recruiting at 4 sites Phase 1 Dana-Farber Cancer Institute · Chicago, Illinois and 3 other locations · NCT03595917

• Extended low-dose prednisone to maintain remission in ANCA-associated vasculitis

  This trial tests whether continuing a low 5 mg daily dose of prednisone for an additional 12 months helps adults with granulomatosis with polyangiitis or microscopic polyangiitis who are in remission after rituximab stay relapse-free.

  Recruiting at 22 sites Hospices Civils de Lyon · Amiens and 44 other locations · NCT03290456

• Combination treatment for relapsed B-cell lymphoma

  This study is testing a new combination of five drugs to see if it can help people with relapsed or hard-to-treat B-cell lymphoma feel better.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03223610

• Comparing vinblastine/prednisone and cytarabine for treating Langerhans Cell Histiocytosis

  This study is testing whether a combination of vinblastine and prednisone works better than cytarabine alone for treating Langerhans Cell Histiocytosis in kids and young adults.

  Recruiting at 10 sites Phase 3 Baylor College of Medicine · Palo Alto, California and 10 other locations · NCT02670707

Quick answers

How many clinical trials of Prednisone are recruiting right now?

35, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (18 trials), China (14 trials), France (2 trials), Australia (1 trial), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 17, Phase 1/2: 6, Phase 4: 3, Phase 3: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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