Condition
High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements clinical trials and research
As of November 12, 2026, Find a Trial lists 4 High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements clinical trials that are recruiting, in United States. By phase: Phase 1/2 (2), Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 1Country
Newest High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Epcoritamab plus dose‑adjusted EPOCH‑R for aggressive B‑cell lymphoma | Phase 2 | Seattle, Washington | Recruiting | Jul 31, 2025 |
| CX-5461 (Pidnarulex) for aggressive B‑cell lymphomas with MYC gene changes | Phase 1/2 | Irvine, California and 7 other locations | Recruiting | Jul 17, 2025 |
| Combining new drugs with standard treatment for relapsed large B-cell lymphoma | Phase 2 | Tucson, Arizona and 103 other locations | Recruiting | Jun 6, 2023 |
| Using inotuzumab ozogamicin with chemotherapy to treat acute lymphoblastic leukemia | Phase 1/2 | Houston, Texas | Recruiting | Jun 13, 2011 |
All recruiting trials (4)
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Epcoritamab plus dose‑adjusted EPOCH‑R for aggressive B‑cell lymphoma
This trial tests whether adding epcoritamab to dose‑adjusted EPOCH‑R chemotherapy can safely improve outcomes for adults with untreated aggressive B‑cell non‑Hodgkin lymphoma.
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CX-5461 (Pidnarulex) for aggressive B‑cell lymphomas with MYC gene changes
This trial tests whether the IV drug CX-5461 (Pidnarulex) is safe and can shrink or control aggressive B‑cell lymphomas that have MYC gene changes in adults who have already had other treatments.
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Combining new drugs with standard treatment for relapsed large B-cell lymphoma
This study is testing a new combination of drugs for people with large B-cell lymphoma that has come back or didn’t get better with earlier treatments to see if it works better than the usual options.
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Using inotuzumab ozogamicin with chemotherapy to treat acute lymphoblastic leukemia
This study is testing if a new drug combined with lighter chemotherapy can help older patients with acute lymphoblastic leukemia who can't handle stronger treatments.
Related topics
Quick answers
How many High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.