Condition

Glomerulonephritis, IGA clinical trials and research

• 6Clinical trials
• 14Countries

Newest Glomerulonephritis, IGA clinical trials

All recruiting trials (6)

• Long-term zigakibart treatment for adults with IgA nephropathy

  Adults with IgA nephropathy who finished an earlier zigakibart trial will receive ongoing subcutaneous zigakibart every two weeks to see if it stays safe and helps over the long term.

  Recruiting at 26 sites Phase 3 Novartis · Denver, Colorado and 25 other locations · NCT06858319

• Iptacopan added to standard care to change kidney biopsy findings in adults with IgA nephropathy

  This will try iptacopan added to standard treatment for adults with biopsy-confirmed IgA nephropathy to see if it reduces mesangial complement (C3c) deposits and improves kidney biomarkers over 9 months.

  Recruiting at 19 sites Phase 2 Novartis · Birmingham, Alabama and 18 other locations · NCT06797518

• Investigating T cell ratios in patients with IgA nephropathy

  This study is testing if measuring certain types of immune cells in the blood can help doctors tell the difference between stable and worsening IgA nephropathy in patients.

  Recruiting Centre Hospitalier Universitaire de Besancon · Besançon · NCT05791162

• Evaluating immunosuppressive therapy for IgA nephropathy in patients with advanced chronic kidney disease

  This study is testing if a combination of low-dose steroids and another medication can help people with IgA nephropathy and advanced kidney disease feel better and manage their symptoms.

  Recruiting Phase 3 Air Force Military Medical University, China · Xi'an · NCT05510323

• Sparsentan for IgA Nephropathy: safety and activity in adults with incident IgAN and recurrent IgAN after transplant

  This trial tests whether sparsentan can be safely given and help kidney outcomes in adults with immunoglobulin A nephropathy, including people newly diagnosed who haven’t had ACEI/ARB therapy and people with recurrent IgAN after kidney transplant.

  Recruiting at 6 sites Phase 2 University of Leicester · Cambridge, England and 5 other locations · NCT04663204

• Data repository for kidney diseases and related conditions

  This study is collecting health information and samples from people with different kidney diseases to see how various factors affect their condition and treatment.

  Recruiting The Rogosin Institute · New York, New York · NCT01802034

Related topics

Quick answers

How many Glomerulonephritis, IGA clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (3 trials), Argentina (2 trials), Malaysia (2 trials), Australia (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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