Condition

Generalized Myasthenia Gravis (gMG) clinical trials and research

• 8Clinical trials
• 14Countries

Newest Generalized Myasthenia Gravis (gMG) clinical trials

All recruiting trials (8)

• Impact of efgartigimod on overall disease experience in adults with generalized myasthenia gravis in Italy

  This study looks at real-world use of efgartigimod in adults with generalized myasthenia gravis to see how it affects their daily symptoms and experiences.

  Recruiting at 30 sites argenx · Acquaviva delle Fonti and 29 other locations · NCT07595653

• ADAPT Forward master protocol testing multiple regimens for generalized myasthenia gravis

  This platform tests several drug regimens, including efgartigimod IV and empasiprubart IV, in adults with generalized myasthenia gravis to find safer and more effective treatment combinations.

  Recruiting at 37 sites argenx · Carlsbad, California and 36 other locations · NCT07294170

• Adding empasiprubart to efgartigimod for AChR-antibody positive generalized myasthenia gravis

  This trial will test whether adding empasiprubart to efgartigimod infusions helps people with AChR-antibody positive generalized myasthenia gravis who have only had a partial response to efgartigimod.

  Recruiting at 33 sites Phase 2 argenx · Carlsbad, California and 32 other locations · NCT07284420

• Treatment approaches for AChR-antibody positive generalized myasthenia gravis in Russia.

  This project will look at which treatments adults in Russia with AChR-antibody positive generalized myasthenia gravis receive and how their symptoms and hospitalizations change over time.

  Recruiting at 7 sites AstraZeneca · Kazan' and 6 other locations · NCT07247279

• Zilucoplan for severe gMG flares that require hospitalization.

  This trial will try daily subcutaneous zilucoplan in adults with AChR-positive generalized myasthenia gravis who are hospitalized for severe flares to see if it quickly improves breathing and bulbar symptoms.

  Recruiting Phase 3 Ohio State University · Tampa, Florida and 2 other locations · NCT07215949

• GC012F CAR‑T infusion for refractory generalized myasthenia gravis

  This trial tests a one-time GC012F CAR‑T cell infusion to see if it helps adults (18–75) with refractory generalized myasthenia gravis who have not responded to standard treatments.

  Recruiting Early Phase 1 Tongji Hospital · Wuhan, Hubei · NCT07058298

• Evaluating CABA-201 for treating generalized myasthenia gravis

  This study is testing a new cell therapy called CABA-201 to see if it can help adults with generalized myasthenia gravis feel stronger and improve their daily function.

  Recruiting at 17 sites Phase 1/2 Cabaletta Bio · Orange, California and 16 other locations · NCT06359041

• Safety of Ultomiris during pregnancy

  This study looks at how safe Ultomiris is for pregnant women and their babies to see if it causes any problems during pregnancy and breastfeeding.

  Recruiting at 4 sites Alexion Pharmaceuticals, Inc. · Boston, Massachusetts and 6 other locations · NCT06312644

Related topics

Quick answers

How many Generalized Myasthenia Gravis (gMG) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (5 trials), Italy (4 trials), Germany (3 trials), Belgium (2 trials), Greece (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 2: 1, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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