Condition

First Line Therapy clinical trials and research

• 4Clinical trials
• 3Countries

Newest First Line Therapy clinical trials

All recruiting trials (4)

• Fruquintinib with trastuzumab and XELOX for first-line treatment of HER2‑positive advanced stomach or GEJ cancer

  This trial will try fruquintinib together with trastuzumab and XELOX to see if it helps people with HER2‑positive advanced stomach or gastroesophageal junction cancer as their first treatment.

  Recruiting Phase 1/2 Henan Cancer Hospital · Zhengzhou, Henan · NCT07334431

• Zanidatamab with pembrolizumab and chemotherapy for HER2- and PD-L1-positive metastatic gastroesophageal adenocarcinoma

  This trial tests whether adding zanidatamab to pembrolizumab plus chemotherapy helps people with untreated HER2- and PD-L1-positive metastatic gastroesophageal adenocarcinoma.

  Recruiting at 14 sites Phase 2 Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Berlin and 19 other locations · NCT07176312

• Low‑dose nivolumab plus chemotherapy as first-line treatment for advanced or metastatic non-small cell lung cancer

  This trial tests whether adding low‑dose nivolumab to standard chemotherapy helps people with advanced or metastatic non‑small cell lung cancer starting first‑line treatment.

  Recruiting Phase 3 Hospital Sultanah Bahiyah · Alor Star, Kedah · NCT07050043

• Comparing two treatment regimens for newly diagnosed acute myeloid leukemia

  This study is testing a new treatment for people with newly diagnosed acute myeloid leukemia to see if it works better than the standard treatment.

  Recruiting Phase 2 Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT06928376

Related topics

Quick answers

How many First Line Therapy clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (2 trials), Germany (1 trial), Malaysia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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