Condition

Esophageal Achalasia clinical trials and research

• 7Clinical trials
• 5Countries

Newest Esophageal Achalasia clinical trials

All recruiting trials (7)

• POEM vs Heller myotomy with Dor fundoplication for achalasia

  This trial tests POEM against laparoscopic Heller myotomy with Dor fundoplication to see which procedure better helps adults with achalasia.

  Recruiting Minia University · Minya, Minya Governorate · NCT07814027

• Comparing Botox and surgery for stomach drainage during esophagectomy

  This study is testing whether Botox injections can help people who have had esophagus surgery manage delayed stomach emptying just as well as surgery can.

  Recruiting Phase 2/3 The Cleveland Clinic · Cleveland, Ohio · NCT06721520

• Investigating the impact of malnutrition on breathing and kidney function in achalasia patients undergoing POEM surgery

  This study is testing how malnutrition affects breathing and kidney health in patients with achalasia who are having a specific surgery called POEM.

  Recruiting Umraniye Education and Research Hospital · Istanbul · NCT06405412

• Evaluating esophageal clearance in achalasia using advanced imaging techniques

  This study is testing if a new way to measure how well the esophagus clears food can replace an older method that uses radiation for patients with achalasia who have had a specific surgery.

  Recruiting University Hospital, Bordeaux · Pessac · NCT06230536

• Comparing routine and symptom-based PPI therapy after a procedure for esophageal achalasia

  This study is testing whether giving patients with esophageal achalasia a routine 12-month prescription for heartburn medication after a specific procedure can help prevent throat inflammation better than only giving the medication when they have symptoms.

  Recruiting at 4 sites Centre Hospitalier Universitaire de Nīmes · Marseille and 3 other locations · NCT05899842

• New treatments for esophageal achalasia

  This study is testing four different treatment options for esophageal achalasia to see which one helps patients feel better, especially those who haven't had success with other treatments.

  Recruiting Medical University of Vienna · Vienna · NCT02518542

• Registry for identifying risk factors of esophageal cancer

  This study is trying to find out if certain blood and tissue markers can help identify people at risk for esophageal cancer by looking at their medical history and samples.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT00260585

Related topics

Quick answers

How many Esophageal Achalasia clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in France (2 trials), United States (2 trials), Turkey (Türkiye) (1 trial), Austria (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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