Condition
Common Variable Immunodeficiency clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Common Variable Immunodeficiency clinical trials that are recruiting, at sites in 2 countries (most in United States (5), France (1)). By phase: Phase 2 (3), Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 2Countries
Newest Common Variable Immunodeficiency clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Peripheral helper T-cells in CVID | — | Pessac | Recruiting | Nov 28, 2025 |
| Using spirometry to manage IgG therapy in patients with Common Variable Immunodeficiency and airway disease | Phase 4 | Birmingham, Alabama | Recruiting | Jan 18, 2022 |
| Using abatacept to treat lung disease in patients with common variable immunodeficiency | Phase 2 | San Francisco, California and 5 other locations | Recruiting | Jun 14, 2021 |
| Stem cell transplant for patients with immune system disorders | Phase 2 | Bethesda, Maryland | Recruiting | Apr 9, 2020 |
| Transplantation of blood or marrow for treating immune system disorders | Phase 2 | Bethesda, Maryland and 1 other locations | Recruiting | Oct 20, 2015 |
| Understanding the natural history of bronchiectasis | — | Bethesda, Maryland | Recruiting | Jul 22, 2009 |
All recruiting trials (6)
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Peripheral helper T-cells in CVID
This study tests whether a type of immune cell called peripheral helper T-cells can help abnormal B cells and influence non-infectious problems in adults with common variable immunodeficiency.
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Using spirometry to manage IgG therapy in patients with Common Variable Immunodeficiency and airway disease
This study is testing if increasing the dose of immunoglobulin therapy can help improve lung function in people with Common Variable Immunodeficiency who have mild to moderate airway problems.
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Using abatacept to treat lung disease in patients with common variable immunodeficiency
This study is testing if a medication called abatacept can help people with common variable immunodeficiency and lung disease feel better.
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Stem cell transplant for patients with immune system disorders
This study is testing if a stem cell transplant from a matched donor can help people aged 4 to 69 with immune system disorders feel better and improve their health.
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Transplantation of blood or marrow for treating immune system disorders
This study is testing if getting blood or marrow transplants from healthy donors can help people aged 4 to 75 with serious immune system disorders feel better and stay healthy.
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Understanding the natural history of bronchiectasis
This study looks at how bronchiectasis develops over time in people with chronic lung infections, especially focusing on genetic and immune factors that might make them more prone to these infections.
Related topics
Quick answers
How many Common Variable Immunodeficiency clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (5 trials), France (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 3, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.