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Cold Exposure clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Cold Exposure clinical trials that are recruiting, at sites in 3 countries (most in United States (2), China (2), United Kingdom (1)). By phase: Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 3Countries
Newest Cold Exposure clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Cold-region exposure and heart remodeling after PCI | — | Beijing, Please Select An Option Below | Recruiting | Aug 19, 2026 |
| Cold exposure with PD-1/PD-L1 immunotherapy in solid tumors | Phase 1 | Chengdu, Sichuan | Recruiting | Apr 20, 2026 |
| High-energy nutrition bars for cold-weather exercise | — | Natick, Massachusetts | Recruiting | Mar 24, 2026 |
| Short cold sessions to grow and activate brown fat | — | Edinburgh | Recruiting | Jul 2, 2025 |
| Effects of fish oil on brown fat activation during cold exposure | — | Bloomington, Indiana | Recruiting | Apr 20, 2023 |
All recruiting trials (5)
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Cold-region exposure and heart remodeling after PCI
This study tests whether long-term cold exposure before PCI is linked to worse heart remodeling and outcomes in people with coronary artery disease.
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Cold exposure with PD-1/PD-L1 immunotherapy in solid tumors
This phase 1 study tests whether adding controlled cold exposure to standard PD-1/PD-L1 therapy is safe and feasible in adults with solid tumors.
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High-energy nutrition bars for cold-weather exercise
This will test whether eating a 350-kcal high-fat versus high-carbohydrate bar helps preserve energy stores and aerobic performance during short cold exposure in physically active adults, including military personnel.
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Short cold sessions to grow and activate brown fat
This study will test whether daily two-hour cold sessions in healthy adults (ages 18–40) change the activity and gene patterns of brown fat, white fat, and muscle.
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Effects of fish oil on brown fat activation during cold exposure
This study is testing if taking fish oil can help healthy young adults better activate their brown fat and stay warm when exposed to cold temperatures.
Related topics
Quick answers
How many Cold Exposure clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), China (2 trials), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.